Effects of the chemical composition of essential oils from seven plants used in traditional medicine in Benin on the growth of eleven pathogenic bacteria in antimicrobial control

Kpadonou, Didier; Kpadonou-Kpoviessi, Bénédicta; Glinma, Bienvenu; Orou, Abdel-Aziz Sina; Agbani, Pierre; Gbaguidi, Fernand; Gbénou, Joachim; Baba-Moussa, Lamine; Kpoviessi, Salomé

doi:10.22271/phyto.2022.v11.i1a.14317

Cited by 6 publications

(4 citation statements)

References 27 publications

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“…Tween 80 (1% v/v) was used as an emulsifier for preparing emulsions of the essential oils in nutrient broth medium with a concentration of 55 μl/ml. Tween 80 was sterilized using 0.22μm Millipore filter (Kpadonou et al, 2022).…”

Section: Essential Oil Emulsion Preparationmentioning

confidence: 99%

Antibacterial potential of essential oils extracted from three medicinal plants against some foodborne bacteria

Serag,

Daadeer,

Elfayoumy

2023

Catrina: The International Journal of Environmental Sciences

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This study aims to evaluate the antibacterial activity of essential oils extracted from the green leaves of three medicinal plants, namely Cupressus macrocarpa, Schinus terebinthifolius, and Eucalyptus citriodora, against selected foodborne bacteria. Gas chromatography/mass spectrometry (GC/MS) analysis was employed to identify the chemical composition of the extracted essential oils. The two main chemical components of C. macrocarpa essential oils (EO) were terpinene-4-ol (32.37%) and citronellol (29.29%). The primary components of S. terebinthifolius EO were α-phellandrene (44.35%) and o-cymene (10.42%). Meanwhile, αphellandrene (13.5%) and sabinene (24.24%) constitute the majority of E. citriodora EO. The antibacterial activity of the essential oils was assessed against Gram-positive bacteria including Bacillus cereus, Staphylococcus saprophyticus, Lysinibacillus fusiformis, and Kocuria rhizophila, as well as the Gram-negative bacterium Serratia liquefaciens. Standard antibiotics like Penicillin, Amoxicillin, and Ampicillin were used for comparison. The results revealed varying degrees of antibacterial activity against each pathogenic isolate used. C. macrocarpa essential oil exhibited the strongest antibacterial action, with a 55.7 mm inhibition zone diameter against Bacillus cereus, which displayed resistance to the tested standard antibiotics. Meanwhile, essential oils of the choosed plants also inhibited the growth of S. liquefaciens despite its tolerance to the tested antibiotics. The minimum inhibitory concentrations (MIC) of C. macrocarpa, S. terebinthifolius, and E. citriodora essential oils ranged from 0.06 to 1.5 mg/ml, 0.68 to 2.0 mg/ml, and 0.2 to 1.77 mg/ml, respectively. These findings highlight the potential of the tested essential oils as antibacterial agents for preserving food materials in a safe, sustainable, cost-effective, and ecofriendly manner.

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Section: Essential Oil Emulsion Preparationmentioning

confidence: 99%

Antibacterial potential of essential oils extracted from three medicinal plants against some foodborne bacteria

Serag,

Daadeer,

Elfayoumy

2023

Catrina: The International Journal of Environmental Sciences

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“…Cassia mimosoides L. (Caesalpiniaceae), is distributed in various countries including Cameroon, Luzon, Mindanao, India, China, Malaysia and Australia. This plant is widely used by tribal people to treat various ailments including typhoid fever and other microbial infections (Kakpo et al, 2019; Malzy, 1954) It is used in Uganda to treat pediatric cough (Namukobe et al, 2011). In northwestern Tanzania, the aerial parts of C. mimosoides are pounded and mixed with animal fat, applied topically or taken orally for fractures, cleaning of the uterus by pregnant women, and as an antibacterial.…”

Section: Introductionmentioning

confidence: 99%

Unravelling the anticancer and enzyme inhibition potential of different classes of compounds including a new steroid, isolated fromCassia mimosoïdes

Tchebou

Farooq

Khan

et al. 2023

Preprint

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The genus Cassia is a significant source of secondary metabolites that are physiologically active and come from several chemical classes. The current research deals with the isolation, spectroscopic elucidation (1D and 2D NMR spectroscopy) and enzymatic activity of fifteen known compounds as well as a new unidentified avenasterol derivative namely 21-methylene-24-ethylidene lophenol. The urease and β-glucosidase inhibitory effects of these compounds were studied for the first time, and molecular docking studies were also performed to verify the structure-activity relationships. All the compounds evaluated towards urease showed higher inhibitory activity (1.224±0.43 < IC50 > 6.678±0.11 μM) compared to standard thiourea (IC50 = 18.61±0.11 μM). Molecular docking results revealed that compound 7 strongly inhibits urease due to the formation of a stable ligand-urease complex via hydrogen bonding, van der Waal and hydrophobic interactions. Formation of a favorable complex of 7 with the target enzyme gave a more negative docking score (-6.95 kcal/mol) than that of thiourea (-3.13 kcal/mol). Regarding the β-glucosidase enzyme, all the compounds evaluated did not show activity except compound 1 which inhibited the latter with a percentage of inhibition of 82.6. These findings imply that this plant may be a contender for developing novel treatments for infectious disorders brought on by urease-producing bacteria.

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“…[10,11] Therefore, the current prevalence of MRSE BSIs has presented a signi cant challenge, prompting the necessity for ongoing research into more effective and secure therapeutic agents. [12] "Traditional or herbal medicines", derived from plants and historically employed in diverse cultures, are commonly perceived as safe when administered in appropriate dosages. [13] Consequently, there is a renewed focus on exploring traditional or herbal medicines as potential alternatives or complementary treatments for emerging and re-emerging multi-drug resistant bacteria .…”

Section: Introductionmentioning

confidence: 99%

The Antibacterial Activity and Mechanism of Emilia Sonchifolia Against Methicillin Resistant Staphylococcus Epidermidis

Liu,

An,

Wang

et al. 2023

Preprint

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Background: Bloodstream infections (BSIs) are a public health concern and cause substantial morbidity and mortality.The pathogen Staphylococcus epidermidis causes a significant number of BSIs. Antibiotics targeting Staphylococcus epidermidis have been the mainstay in BSIs. However, Conventional antibiotics have been eclipsed in combating with drug-resistant bacteria. Alternate ways of treating these antibiotic-resistant infections are thus urgently needed. Numerous studies have demonstrated that certain Chinese medicines exhibit notable antimicrobial activity and possess the ability to impede the development of bacterial resistance. Based on an extensive body of research in the field of traditional Chinese medicine(TCM), it has been determined that the Compositae plant exhibits a noteworthy anti-Methicillin-Resistant Staphylococcus Epidermidis (MRSE) effect. Methods: Initially, the Compositae plant Emilia sonchifolia underwent a screening process, followed by crushing and extraction using water. Subsequently, the extract was concentrated based on a specific ratio, dried, partitioned, and subsequently prepared for utilization.Therefore, the objective of this study was to examine the antibacterial efficacy and underlying antibacterial mechanism of Emilia sonchifolia against methicillin-resistant Staphylococcus epidermidis( MRSE). The antibacterial activity of Emilia sonchifolia against MRSE was assessed through in vitro tests measuring minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC). Furthermore, the antibacterial activity of Emilia sonchifolia against MRSE was evaluated in vivo using a mouse bloodstream infections model. Additionally, various aspects such as bacteria cell morphology and energy metabolism and defense mechanisms were investigated to explore the underlying antibacterial mechanisms of Emilia sonchifolia. Results: The results showed that MIC and MBC values of Emilia sonchifolia against MRSE were 5mg/mL and 20mg/mL, respectively. Meanwhile, Emilia sonchifolia can effectively treat MRSE induced bloodstream infections. Furthermore, the utilization of scanning electron microscopy and transmission electron microscopy techniques unveiled that the administration of Emilia sonchifolia induced alterations in the cellular structure of MRSE, leading to the disruption of both cell wall and membrane integrity. Additionally, exposure to Emilia sonchifolia resulted in a decrease in the enzymatic activities of succinate dehydrogenase, NADP-malate dehydrogenase, catalase, and superoxide dismutase. Conclusions: Thus, the aforementioned observations have contributed novel insights into the mechanistic understanding of Emilia sonchifolia's efficacy against MRSE, thereby offering potential strategies for managing MRSE infections.

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Effects of the chemical composition of essential oils from seven plants used in traditional medicine in Benin on the growth of eleven pathogenic bacteria in antimicrobial control

Cited by 6 publications

References 27 publications

Antibacterial potential of essential oils extracted from three medicinal plants against some foodborne bacteria

Antibacterial potential of essential oils extracted from three medicinal plants against some foodborne bacteria

Unravelling the anticancer and enzyme inhibition potential of different classes of compounds including a new steroid, isolated fromCassia mimosoïdes

The Antibacterial Activity and Mechanism of Emilia Sonchifolia Against Methicillin Resistant Staphylococcus Epidermidis

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