Effects of the environmental endocrine disrupting compound benzo[a]pyrene on thyroidal status of abu mullet (Liza abu) during short-term exposure

Abstract

HighlightsThe half-life of BaP is 3–4 days and then it metabolized in the liver.BaP concentration in the muscle of treated fish reached a maximum level after 4 days.Exposure of fish to BaP resulted in a decrease in T3 and T4 plasma levels up to day 4.Exposure of fish to BaP resulted in an increase in TSH plasma level up to day 4.

Assessment of reproductive and developmental effects of graphene oxide on Japanese medaka (Oryzias latipes)

“…We observed after sonication GO was agglomerated in the water over time, however, because of the negative value of zeta potential (−30.5 mV) the solution was considered stable (Patlolla et al, 2017). Although the conventional method of exposure to nanomaterials in fish is immersion, direct administration of GO or EDCs by ip-injection(s) have also been reported (Zhang et al, 2002;Kiparissis et al, 2003;Dang 2016;Dorelle et al, 2017;Movahedinia et al, 2018;Dang and Kienzler, 2019;Paital et al 2019). To avoid agglomeration of GO in the environment, we preferred to use ip injection as an alternative method, because the route of administration of nanomaterials has significant impact on the retention and biological function of the compounds (Ema et al, 2016).…”

Adolescence benzo[a]pyrene treatment induces learning and memory impairment and anxiolytic like behavioral response altering neuronal morphology of hippocampus in adult male Wistar rats

“…B[a]P is a potent neurotoxicant with high affinity for lipid-rich tissues such as brain, it enters into the brain tissues and enhances the generation of reactive oxygen species (ROS), resulting significant changes in mood behaviour [5]. Moreover, when exposed to high levels, B[a]P affects thyroid function in fish [6] and its metabolites tend to accumulate both in the blood and brain [7], thus causing neurological impairments [8]. Early exposure to PAHs may adversely affect children’s IQ, cognitive development and increased behavioral problems [[8], [9], [10], [11]].…”

OctylPhenol (OP) Alone and in Combination with NonylPhenol (NP) Alters the Structure and the Function of Thyroid Gland of the Lizard Podarcis siculus

“…Structurally, lizards exposed to OP and OP + NP showed a reduced height of the follicular epithelium and a retracted colloid with fewer reabsorption vacuoles. Follicular epithelium height and colloid are indices of secretory activity of the gland (Movahedinia et al 2018 ) as well as useful parameters for the observation of EDC morphological effects on the thyroid. Moreover, epithelial cell height is a histological method of thyroid gland assessment as it is considered to be roughly proportional to the degree of response to thyroid-stimulating hormone (TSH) (Moccia et al 1981 ).…”