2001
DOI: 10.1248/jhs.47.107
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Effects of the Oral Administration of Green Tea Polyphenol and Tannic Acid on Serum and Hepatic Lipid Contents and Fecal Steroid Excretion in Rats.

Abstract: Green tea polyphenol (Polyphenon) or tannic acid was administered orally to rats at a dose of 0.01-1.0 or 0.1-1.0 g/kg for 23 days, and changes both in serum and hepatic lipid concentrations and in fecal steroid excretion were examined. The administration of 0.2-1.0 g/kg of Polyphenon caused a significant decrease in levels of serum HDLcholesterol, whereas tannic acid had no significant effect on serum lipid concentrations. The hepatic triglyceride concentration was significantly higher than controls in rats g… Show more

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Cited by 27 publications
(19 citation statements)
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“…They have been recognized as functionally active molecules, possessing antioxidant, anticancer, antimutagenic properties, as well as exerting protective effects against several other diseases (Ferguson, 2001;Nakamura et al, 2001). Reports from our laboratory have also confirmed antioxidative, antigenotoxic and anti-tumor promotion role of tannic acid (Sehrawat et al, 2006;Ahmad and Sultana, 2012).…”
mentioning
confidence: 52%
“…They have been recognized as functionally active molecules, possessing antioxidant, anticancer, antimutagenic properties, as well as exerting protective effects against several other diseases (Ferguson, 2001;Nakamura et al, 2001). Reports from our laboratory have also confirmed antioxidative, antigenotoxic and anti-tumor promotion role of tannic acid (Sehrawat et al, 2006;Ahmad and Sultana, 2012).…”
mentioning
confidence: 52%
“…The higher apparent protein digestibility coefficients observed in rats fed on 18% CP diets support these results. Nakamura et al (2001) suggest that TA at a dose of only 0.1 g/kg of body weight causes a reduction of liveweight gain of rats. This response may result from a negative influence of TA on nutrient digestibility and absorption.…”
Section: Discussionmentioning
confidence: 94%
“…Analytical Methods ---Serum concentrations of total and high density lipoprotein (HDL)-cholesterol), triglycerides, phospholipids and TBARS and contents of total cholesterol, triglycerides and phospholipids in the liver were analyzed as described previously. 32) Collected feces were dried overnight at 60°C and ground to a powder. Fecal neutral steroids and bile acids were determined by GC-FID as described previously.…”
Section: Methodsmentioning
confidence: 99%