Effects of the Sangvia blood collection system on patients undergoing elective hip surgery

Teetzmann, Ralf; Sørensen, Betina Bang; Liseth, Knut; Opheim, Elin Netland; Hervig, Tor

doi:10.1016/j.transci.2014.08.004

Cited by 2 publications

(4 citation statements)

References 45 publications

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“…Recently, Thomassen et al examined 575 patients who underwent primary hip and knee replacement with autotransfusion or no drainage [ 23 ]. The authors did not identify any significant difference in the need for ABT between the groups, which is in accordance with our results and those of many other studies (e.g., [ 13 , 18 , 22 , 24 , 32 , 33 ]. Although the autotransfusion group had a significant reduction of ABT rate compared with the regular drainage/no drainage group in our meta-analysis, it is clear that autotransfusion drainage and no drainage have similar effects on ABT reduction.…”

Section: Discussionsupporting

confidence: 93%

“…Seventeen RCTs [ 2 , 7 , 12 – 18 , 22 – 24 , 29 – 33 ] were assessed and 2314 patients were included in the meta-analysis (Table 1 ). Sample sizes ranged from 36 to 231.…”

Section: Resultsmentioning

confidence: 99%

“…Anticoagulants and tourniquets would affect blood loss during total joint arthroplasty. Second, two new RCTs were published [ 22 , 23 ], neither of which showed a significant effect of the autotransfusion system compared with no drainage. In addition, few systematic reviews have considered the differences between autotransfusion drainage and no drainage for both TKA and THA.…”

Section: Discussionmentioning

confidence: 99%

“…Drains are used to prevent hematoma accumulation and decrease the possibility of prolonged wound healing and infection [ 21 ]. Recent studies have reported that the transfusion of autologous blood has no effect in the majority of cases, but some studies support the method [ 22 – 24 ]. Furthermore, the usefulness of autotransfusion is uncertain due to methodological difficulties, such as no formal power analysis for study size and significance level, different transfusion triggers, and different autotransfusion devices [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

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Application of postoperative autotransfusion in total joint arthroplasty reduces allogeneic blood requirements: a meta-analysis of randomized controlled trials

Lin

Zhang

et al. 2017

BMC Musculoskelet Disord

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BackgroundTotal joint arthroplasty is associated with significant blood loss and often requires blood transfusion. However, allogeneic blood transfusion (ABT) may lead to severe problems, such as immunoreaction and infection. Postoperative autotransfusion, an alternative to ABT, is controversial. We conducted a meta-analysis to evaluate the ability of postoperative autotransfusion to reduce the need for ABT following total knee arthroplasty (TKA) and total hip arthroplasty (THA).MethodsSystematic literature searches for randomized controlled trials were performed using PubMed, Embase, and the Cochrane Library until February 2016. Relative risks (RRs) and weighted mean differences with 95% confidence intervals (CIs) were calculated using fixed-effect or random-effect models; we also evaluated publication bias and heterogeneity.ResultsSeventeen trials with a total of 2314 patients were included in the meta-analysis. The pooled RRs of ABT rate between autotransfusion and the regular drainage/no drainage groups for TKA and THA were 0.446 (95% CI = 0.287, 0.693; p < 0.001) and 0.757 (95% CI = 0.599, 0.958; p = 0.020), respectively. In the subgroup analysis performed in TKA patients according to control interventions, the pooled RRs were 0.377 (95% CI = 0.224, 0.634; p < 0.001) (compared with regular drainage) and 0.804 (95% CI = 0.453, 1.426, p = 0.456) (compared with no drainage). In the subgroup analysis performed for THA, the pooled RRs were 0.536 (95% CI = 0.379, 0.757, p < 0.001) (compared with regular drainage) and 1.020 (95% CI = 0.740, 1.405, p = 0.904) (compared with no drainage).ConclusionsCompared to regular drainage, autotransfusion reduces the need for ABT following TKA and THA. This reduction is not present when comparing autotransfusion to no drainage. However, the reliability of the meta-analytic results concerning TKA was limited by significant heterogeneity in methods among the included studies.Electronic supplementary materialThe online version of this article (doi:10.1186/s12891-017-1710-2) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 93%

“…Seventeen RCTs [ 2 , 7 , 12 – 18 , 22 – 24 , 29 – 33 ] were assessed and 2314 patients were included in the meta-analysis (Table 1 ). Sample sizes ranged from 36 to 231.…”

Section: Resultsmentioning

confidence: 99%