Effects of three Mexican medicinal plants (Asteraceae) on blood glucose levels in healthy mice and rabbits

Alarcón-Aguilar, Francisco Javier; Román-Ramos, Rubén; Jiménez-Estrada, Manuel; Reyes-Chilpa, Ricardo; Gonzalez-Paredes, B.; Flores-Saenz, José Luis

doi:10.1016/s0378-8741(96)01494-8

Cited by 62 publications

(40 citation statements)

References 10 publications

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“…These results indicate that peltalosa has a hypoglycemic activity on mice with mild diabetes, but this activity diminished on mice with severe diabetes (Table 2). It is likely that the hypoglycemic effect is similar to tolbutamide, and possibly due to an enhanced secretion of insulin from the islets of Langerhans or an increased utilization of The herein reported hypoglycemic activity in P. peltatum agrees with previously reported results, [3][4][5][6] in which the traditional preparation (aqueous decoction) of this plant showed significant hypoglycemic effect in temporarily and alloxan hyperglycemic rabbits, as well as in healthy and alloxan diabetic mice. We recently also studied the hypoglycemic activity of four extracts obtained from the roots and rhizomes of P. peltatum (hexane, chloroform, methanol, and water extracts), concluding that the two most polar extracts exhibited hypoglycemic activity in healthy mice.…”

supporting

confidence: 90%

Hypoglycemic Activity of a New Carbohydrate Isolated from the Roots of Psacalium peltatum

Contreras

Roman

Pérez

et al. 2005

CHEMICAL & PHARMACEUTICAL BULLETIN

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supporting

confidence: 90%

Hypoglycemic Activity of a New Carbohydrate Isolated from the Roots of Psacalium peltatum

Contreras

Roman

Pérez

et al. 2005

CHEMICAL & PHARMACEUTICAL BULLETIN

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“…When consumers cannot purchase P. decompositum in the markets of central Mexico, a local matarique ( Psacalium peltatum ) is substituted. Even though P. decompositum exhibited greater hypoglycemic activity than other members of the complex [ 58 ], its presence in the market has declined attributable to its scarcity due to overcollection.…”

Section: Plant Complexes In the Marketsmentioning

confidence: 99%

Traditional Markets in Mesoamerica: A Mosaic of History and Traditions

Linares

Bye

2016

Ethnobotany of Mexico

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This contribution discusses the different types of markets, tianguis (traditional producer markets) and trade relations which have occurred in Mexico in different historical periods. The comparison of such major pre-Hispanic cultures as the Aztecs, Mayas, and Purépecha highlight the role of the long-distance traders or pochteca . During the Viceroyalty Period, alcabalas (taxes) registered in the documents reveal the continuity of the trade routes based on pre-Hispanic roads and exchange of products from different ecological zones. For Independent Mexico Period, the commercial circuits that supplied urban areas are characterized by those of Puebla. This analysis suggests that the marketing in contemporary Mexico is a consequence of the relationships established during the different historical periods. These relationships are refl ected in the tianguis and contemporary markets as well as products today. The exchange and marketing chains have been infl uenced and driven by transportation systems, such as the train network at the time of the Porfi riato Period, and currently by the highway systems and mechanized transport vehicles. As a result, today's exchange system is characterized by a larger scale, a greater distance and the phenomenon of the central markets while tianguis are located in peripheral circuits. The botanical products that are sold and exchanged in the commercial circuits refl ect the cultural exchange, based on traditional knowledge, and the exploitation of the natural resources from different ecological zones. Contemporary Mexican studies illustrate the infl uence of the central market on the demand of plants with novel applications and draw attention to the danger of the overcollection of wild species due to the effect of the emerging demands, hence defending the need for conservation of natural habitats.

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“…A total of about 35,000 plant species are being used for medicinal purposes through-out the world. Considering the plants with medicinal values, Asteraceae is the largest family of flowering plants and renowned for its traditional medicine properties like Wedelia calendulacea plant possessing hepato-protective activity in which it revitalizes the liver and is used to treat liver dysfunction [1], methanol extracts of Wedelia trilobata are known to be having potent antioxidant and anti-bacterial activity [2], Vernonia cinerea used as an therapeutic agent in malarial fever and various gastro-intestinal disorders [3,4], Bidens alba possess anti-malarial activity in its ethanol extracts [5], Acourtia thurberi has shown reduction of the blood sugar level in mice [6], Jurinea consanguinea and Evax pygmaea are the other Asteraceae family plants having antioxidant properties [7,8].…”

Section: Introductionmentioning

confidence: 99%

Methanolic Extract of Wedelia trilobata in Antiproliferation and Apoptotic Activity

Venkatesh¹,

Kollur²,

Javarashetty³

et al. 2016

Nat Prod Chem Res

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Herein, we report extraction of biologically important isolates from medicinally valuable plant Wedelia trilobata. The biological activities viz., anti-proliferative activity and cytotoxic effect of the methanolic extract of Wedelia trilobata was investigated by Thymidine uptake assay, wound healing assay and MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, respectively. In addition, apoptotic activity was also examined through nuclear staining and DNA fragmentation assays. The IC 50 value of the methanolic extract for the growth inhibition of MEG-01 cells was found to be 80 μg/ml under which the normal HEK-293 cells were resistant to the toxic effect. Concentration and time dependent studies in Thymidine uptake and wound healing assays revealed the prominent antiproliferative activity against MEG-01 at the concentration of 80 μg/ml for 48 h. The nuclear staining and DNA fragmentation assays also confirmed that the methanolic extract induces apoptosis in MEG-01 cells.

show abstract

Effects of three Mexican medicinal plants (Asteraceae) on blood glucose levels in healthy mice and rabbits

Cited by 62 publications

References 10 publications

Hypoglycemic Activity of a New Carbohydrate Isolated from the Roots of Psacalium peltatum

Hypoglycemic Activity of a New Carbohydrate Isolated from the Roots of Psacalium peltatum

Traditional Markets in Mesoamerica: A Mosaic of History and Traditions

Methanolic Extract of Wedelia trilobata in Antiproliferation and Apoptotic Activity

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