This study endeavored to analyze the progress made to meet the Sustainable Development Goals in terms of resource use, sustainable production and consumption, and the triple planetary crisis (i.e., climate change, biodiversity loss, and pollutant emissions) at the national and regional levels in Asia. The study highlighted that the progress toward sustainable consumption and production is still not sufficient to meet the ambitious national targets. An urgent need for a comprehensive approach to address climate change, biodiversity loss, pollutant emissions, and resource use has been ascertained. China’s greenhouse gas emissions have surged tremendously. India is also endeavoring to decouple emissions from growth via renewable energy. Vulnerable Pakistan seeks emission reduction and financial aid. Indonesia, Thailand, and Vietnam outline emission reduction strategies. Land use change emerges as a key biodiversity loss driver, stressing the need for sustainable land policies and conservation. Material consumption highlights the call for production optimization, circular economies, and innovative technology. Energy’s role in development requires decoupling from growth through efficiency, renewables, and eco-friendly paths. Freshwater needs careful management for sustainability, and international collaboration and policy reform are urged for global water use efficiency. Decoupling trends between growth, resource use, and environmental impact show a complex pattern, with the feasibility of absolute decoupling limited by growth interdependence.