Effects of transcranial direct current stimulation on lower limb function, balance and quality of life after stroke: a systematic review and meta-analysis

Lima, Eloise de Oliveira; Neto, José Maurício Ramos de Souza; Andrade, Suellen Marinho

doi:10.1080/01616412.2023.2211457

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…Similarly, Klomjai and Aneksan [106] found no significant lower limb performance improvements when dual-tDCS was applied during physical therapy. Additionally, recent reviews showed that tDCS had limited effects in an isolated treatment environment, but it is possible to improve lower limb functions when combined with other therapies [106][107][108][109].…”

Section: Challenges In Transcranial Electrical Stimulation (Tes)mentioning

confidence: 99%

Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review

Meng,

Houston,

Zhang

et al. 2024

Brain Sciences

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Introduction: Stroke survivors often have motor impairments and related functional deficits. Transcranial Electrical Stimulation (tES) is a rapidly evolving field that offers a wide range of capabilities for modulating brain function, and it is safe and inexpensive. It has the potential for widespread use for post-stroke motor recovery. Transcranial Direct Current Stimulation (tDCS), Transcranial Alternating Current Stimulation (tACS), and Transcranial Random Noise Stimulation (tRNS) are three recognized tES techniques that have gained substantial attention in recent years but have different mechanisms of action. tDCS has been widely used in stroke motor rehabilitation, while applications of tACS and tRNS are very limited. The tDCS protocols could vary significantly, and outcomes are heterogeneous. Purpose: the current review attempted to explore the mechanisms underlying commonly employed tES techniques and evaluate their prospective advantages and challenges for their applications in motor recovery after stroke. Conclusion: tDCS could depolarize and hyperpolarize the potentials of cortical motor neurons, while tACS and tRNS could target specific brain rhythms and entrain neural networks. Despite the extensive use of tDCS, the complexity of neural networks calls for more sophisticated modifications like tACS and tRNS.

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Section: Challenges In Transcranial Electrical Stimulation (Tes)mentioning

confidence: 99%

Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review

Meng,

Houston,

Zhang

et al. 2024

Brain Sciences

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show abstract

“…A recent systematic review encompassing 19 studies revealed that active tDCS in isolation, regardless of the stimulation mode, did not significantly enhance lower extremity motor function in patients with stroke when compared with sham tDCS [ 19 ]. However, subgroup analysis showed a notable difference in favor of tDCS during the acute and subacute phases with a low quality of evidence.…”

Section: Introductionmentioning

confidence: 99%

“…Transauricular VNS (taVNS) is a non-invasive VNS technique that stimulates the afferent auricular branch of the vagus nerve located at the tragus in the external ear [ 19 ]. Recent studies have reported the modulatory effects of taVNS on motor cortex excitability, which is thought to be linked to GABAergic intracortical inhibition [ 25 26 ].…”

Section: Introductionmentioning

confidence: 99%

Update on Non-invasive Brain Stimulation on Stroke Motor Impairment: A Narrative Review

Kim,

Park

2024

Brain Neurorehabil

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Stroke is a leading global cause of death and disability, with motor impairment being one of the common post-stroke complications. Rehabilitation is crucial for functional recovery. Recently, non-invasive brain stimulation (NIBS) has emerged as a promising intervention that allows neuromodulation by activating or inhibiting neural activity in specific brain regions. This narrative review aims to examine current research on the effects of various NIBS techniques, including repetitive transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation, and transcranial focused ultrasound on post-stroke motor function.

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Effects of treadmill training combined with transcranial direct current stimulation on mobility, motor performance, balance function, and other brain-related outcomes in stroke survivors: a systematic review and meta-analysis

Usman,

Wong,

2024

Neurol Sci

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Introduction Treadmill training (TT) is a gait training technique that has commonly been used in neurorehabilitation, and has positive effects on gait, mobility, and related outcomes in stroke survivors. Transcranial direct current stimulation (tDCS) is a non-invasive approach for modulating brain cortex excitability. Aim To evaluate the available scientific evidence on the effects of TT combined with tDCS on mobility, motor performance, balance function, and brain-related outcomes in stroke survivors. Methods Five databases namely the Cochrane library, PEDro, Web of Science, PubMed, and EMBASE, were searched for relevant studies from inception to March, 2024. Only randomized controlled trials were included, and their methodological quality and risk of bias (ROB) were evaluated using the PEDro scale and Cochrane ROB assessment tool respectively. Qualitative and quantitative syntheses (using fixed effects meta-analysis) were employed to analyze the data. Results The results revealed that TT combined with active tDCS had significant beneficial effects on some mobility parameters, some gait spatiotemporal parameters, some gait kinematic parameters, gait endurance, gait ability, and corticomotor excitability in stroke survivors, but no significant difference on gait speed (P > 0.05), functional mobility (P > 0.05), motor performance (P > 0.05), or some balance functions (P > 0.05), compared with the control conditions. Conclusions TT combined with active tDCS significantly improves some gait/mobility outcomes and corticomotor excitability in stroke survivors.

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Effects of transcranial direct current stimulation on lower limb function, balance and quality of life after stroke: a systematic review and meta-analysis

Cited by 4 publications

References 33 publications

Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review

Exploring the Prospects of Transcranial Electrical Stimulation (tES) as a Therapeutic Intervention for Post-Stroke Motor Recovery: A Narrative Review

Update on Non-invasive Brain Stimulation on Stroke Motor Impairment: A Narrative Review

Effects of treadmill training combined with transcranial direct current stimulation on mobility, motor performance, balance function, and other brain-related outcomes in stroke survivors: a systematic review and meta-analysis

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