2022
DOI: 10.3390/toxics10080423
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Effects of Two Antiretroviral Drugs on the Crustacean Daphnia magna in River Water

Abstract: Antiretroviral (ARVs) drugs are used to manage the human immunodeficiency virus (HIV) disease and are increasingly being detected in the aquatic environment. However, little is known about their effects on non-target aquatic organisms. Here, Daphnia magna neonates were exposed to Efavirenz (EFV) and Tenofovir (TFV) ARVs at 62.5–1000 µg/L for 48 h in river water. The endpoints assessed were mortality, immobilization, and biochemical biomarkers (catalase (CAT), glutathione S-transferase (GST), and malondialdehyd… Show more

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Cited by 7 publications
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“…Biochemical parameters can be categorized as enzymatic or non-enzymatic. Quantitative studies on enzyme activity variations in D. magna have been conducted to determine the ecological risk of chemicals [ 25 , 26 , 27 ].…”
Section: Introductionmentioning
confidence: 99%
“…Biochemical parameters can be categorized as enzymatic or non-enzymatic. Quantitative studies on enzyme activity variations in D. magna have been conducted to determine the ecological risk of chemicals [ 25 , 26 , 27 ].…”
Section: Introductionmentioning
confidence: 99%