Effects of Ultrasonic Vibrations on Nerve Tissues.

Abstract

A relatively simple technic for the intraspinal inoculation of mice which lends itself to routine laboratory use has been described. For Lansing poliomyelitis virus, it seems to be a more sensitive method of detecting virus than the intracerebral technic. The quantitation of virus titers by this method is consistent between two different technicians and on re-peated tests by one technician from anyone i set of virus dilutions. It can be applied to the routine testing of serums for Lansing antibodies. The chief advantage of the technic is the marked shortening of the incubation period of Lansing infection in mice as compared to that following intracerebral inoculation.

Potential Adverse Ultrasound-related Biological Effects

“…99,100 Ultrasound exposure to the lumbar plexus causes hind limb paralysis in experimental animals. 101 Hind limb paralysis was observed at room temperature after a 4.3-s ultrasound exposure (35 W/cm 2 ) to the lumbar area, but more prolonged exposure duration (7.3 s) was required to produce similar neurologic damage at cooler temperatures (1-2°C). 101 Histologic analysis revealed neuronal and myelin destruction in the spinal cord, and axonal degeneration, chromatolysis, pyknosis with intact mesenchymal structures, and clumping of myelin in the peripheral nerves and cauda equina.…”

Effect of the gel elasticity of model skin matrices on the distance/depth‐dependent transmission of vibration energy supplied from a cosmetic vibrator

“…Hand-related injuries were most common disorders [2], which were closely related to nervous system dysfunction. Prolonged and repeated exposure to hand-transmitted vibration can injure nerve tissues [3], arteries [4] and peripheral vessels [5]. An electron microscopy study also confirmed associated injury to peripheral nerves [6].…”

Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis

“…In 1958, Fry et al showed in vivo the reversible suppression of the sensory-evoked potentials in the central nervous system by the ultrasound [ 26 ]. Exposure of the cat lateral geniculate nucleus (LGN) to focused ultrasound (980 kHz) through a cranial window produced reversible suppression of the light-evoked potentials by over 67%, and the complete recovery took about 30 min [ 26 , 27 , 28 , 29 ]. In 1976, Gavrilov et al demonstrated in human that the focused ultrasonic stimulation ranging from 0.48 to 2.67 MHz excited a variety of superficial and deep peripheral nerves, such as those mediating thermal, pain, and tactile sensations [ 30 ].…”