Wake Forest UniversBySt/mmary.-This study tested the hypothesis that the depression of barpressing following hypertonic NaCl stomach loads is due to their producing unconditioned drive stimuli. Ir was predicted rhar rats given a response-depressing load repeatedly would show less depression on successive occasions as the novel drive stimuli became conditioned to the response. The resulrs did not support this prediction.According to drive stimulus theory responses become conditioned to specific internal stimuli which are produced by particular deprivation conditions. If these internal stimulus conditions are altered, S is less likely to make the response conditioned to them. Estes' (1958) "stimulus-response theory of drive" predicts this by assuming :hat the conditioned stimuli in such a test situation make up a smaller proportion of the total stimuli than they had during prior training. In other words, there are relatively fewer conditioned stimulus elements in the test situation to evoke the response. Such theorizing accounts for satiation effects but also makes the more interesting prediction that as the length of deprivation in a test periad is lolzge~ than in the uaining periods S should also respond less. Supporting this view, Birch, Burnstein, and Clark ( 1958) reported that rats normally fed only zt a specific time each day responded more for food at that time than at shorter or longer deprivation periods. Brown and Belloni ( 1963), however, corrected for a number of deficiencies in the Birch experiment and were unable to replicate [he results. Hatton (1965) used NaCl stomach loads to increase test drive level above that of the training level. Rats were trained to bar-press for water while 23.5-hr. water deprived, then were extinguished after water or hypertonic loads. He obtained an inverted-U function, extinction being more rapid as a function of volume of water load or concenuation of NaCl load. Saline loads which produce more drinking were at the same time more inhibiting to bar-pressing. Since each S received only a single stomach load, Hatton interpreted the depressive effect of NaCl as the result of a change in drive stimuli, conditioned drive stimuli having been replaced by the unconditioned stimuli evoked by the NaC1. Other investigators have reported depressive effects of NaCl loads which might be interpreted in the same manner (e.g., Beck, 1963;Beck & McLean, 1967).In the present experiment rats were given the same response-depressing saline stomach load prior to bar-pressing on 4 different days. It was predicted