Effects of various parameters on ultrasonic comminution of coal in water media

Şahinoğlu, Ercan; Uslu, T.

doi:10.1016/j.fuproc.2015.03.028

Cited by 19 publications

(5 citation statements)

References 20 publications

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“…On the other hand, at higher ultrasonic power levels, intensity of cavitation increases due to increase in number of bubbles for cavitation. Higher energy is consumed for breakage (Sahinoglu and Uslu 2015). Based on our test results, it can be concluded that, in contrast to the expected, the particle size of the product obtained increases with an increase in the amplitude.…”

Section: Effect Of Ultrasonic Power On Particle Size and Width Of Psdmentioning

confidence: 44%

Preparation of submicron calcite particles by combined wet stirred media milling and ultrasonic treatment

Toraman

Inal

2016

Particulate Science and Technology

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This paper investigates the grindability of calcite powder (D50 = 6.68 µm) to sub-micron particle sizes using stirred media mill (0.75 l) and ultrasonic generator (400 W, 24 kHz). The present study focuses directly on the comminution of calcite powder in water media by combined stirred milling and ultrasonic treatment and effects of some operational parameters such as grinding time (10-30 min), ultrasonic power (40-100% µm as amplitude settings) and solid ratio (10-30% w/w) on comminution. Experimental results have been evaluated on the basis of product size and width of particle size distribution (PSD).

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Section: Effect Of Ultrasonic Power On Particle Size and Width Of Psdmentioning

confidence: 44%

Preparation of submicron calcite particles by combined wet stirred media milling and ultrasonic treatment

Toraman

Inal

2016

Particulate Science and Technology

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“…They also confirmed a positive effect of the comminution degree of brittle materials on the shape of their particles under mechanical grinding in an electro-hydraulic mill [41]. On the other hand, the tests showed a limited usefulness of ultrasound treatment for coal comminution in an aqueous environment [42]. Still, the usefulness of a fractal model to characterize the degree of the particle size distribution of coal [37] comminuted in a hydro-jet mill was positively evaluated.…”

Section: Introductionmentioning

confidence: 67%

Micronization of Hard Coal with the Use of a High-Pressure Water Jet

Borkowski

Szada-Borzyszkowski

2021

Energies

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This paper presents an original method for the micronization of coal particles in a hydro-jet mill, which allows effective comminuting of coal in the pressure range of 100–250 MPa, at a variable water flow rate of 0.2–0.5 dm3/s. The discussed high-pressure water jet mill (HPWJM) allows the comminution of standard fines, with a grain size up to 2 mm, and at a relatively high comminuting efficiency of 8 to 55 g/s. In addition, the paper presents energy-consumption ratios, and indicates the advantage of this method over mechanical grinding in a planetary ball-mill. At optimum conditions, coal comminution at an efficiency of Qc = 38.4 g/s and at an energy input of EH = 1.1 MJ/kg provides an average particle size of about 40 µm. The degree of comminution was further improved by applying roto-turbulent micronization, which resulted in an average size of comminuted coal particles of only 17 µm. As an additional result, the actual surface area of the particles increased by 10–30 thousand times when compared to ground fines—this fact is of significance for the application of micronized particles in quasi-liquid coal-water fuel.

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“…Additionally, an intense agitation could prevent the agglomeration of immature NPs more successfully and produced particles with a smaller size . On the other hand, at a higher power of ultrasound, the intensity of particle–cavitation interactions could increase and result in a reduced particle size of the NPs . Based on these observations, the ratio between DMSO:H 2 O of 0.5:2, stirring rate of 800 rpm, and ultrasonic power of 195 W were considered as optimal process parameters, yielding smaller size particles of PULL–CC–PTX NPs and PULL–SS–PTX NPs (118 and 134 nm, respectively) with a unimodal size distribution (PDI values, 0.183 and 0.149, respectively) (Figure S2, Table S1, and Table ).…”

Section: Resultsmentioning

confidence: 99%

“…39 On the other hand, at a higher power of ultrasound, the intensity of particle−cavitation interactions could increase and result in a reduced particle size of the NPs. 40 Based on these observations, the ratio between DMSO:H 2 O of 0.5:2, stirring rate of 800 rpm, and ultrasonic power of 195 W were considered as optimal process parameters, yielding smaller size particles of PULL−CC−PTX NPs and PULL−SS−PTX NPs (118 and 134 nm, respectively) with a unimodal size distribution (PDI values, 0.183 and 0.149, respectively) (Figure S2, Table S1, and Table 1). Their zeta potential values were about −12 mV, indicating the existence of anionic CM−PULL residues on the outer layers of the NPs.…”

Section: Synthesis and Characterization Of Pull−cc−ptx And Pull−ss−ptxmentioning

confidence: 99%

Engineering Transferrin-Decorated Pullulan-Based Prodrug Nanoparticles for Redox Responsive Paclitaxel Delivery to Metastatic Lung Cancer Cells

Zhao

Guo

Bera

et al. 2023

ACS Appl. Mater. Interfaces

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Paclitaxel (PTX) remains a cornerstone in the treatment of locally advanced and metastatic lung cancer. To improve its therapeutic indices against lung cancer, novel redox-sensitive pullulan/PTX-based prodrug NPs (PULL–SS–PTX NPs) were accomplished, which were further surface-decorated with transferrin (TF), a cancer cell-targeting ligand, to afford TF–PULL–SS–PTX NPs. These prodrug NPs (drug content, >37% and average size, 134–163 nm) rapidly dismantled their self-assembled architecture upon exposure to simulated reducing conditions, causing a triggered drug release as compared to the control scaffold (PULL–CC–PTX NPs). These scaffolds also evidenced outstanding colloidal stability, cellular uptake efficiency, and discriminating cytotoxicity between the cancer and healthy cells. Intravenously delivered redox-sensitive NPs exhibited improved tumor-suppressing properties as compared to the control nanovesicles (PULL–CC–PTX NPs) in a B16–F10 melanoma lung metastasis mice model. The targeting efficiency and associated augmented anticancer potentials of TF–PULL–SS–PTX NPs relative to TF-free redox-responsive NPs and Taxol intravenous injection were also established on the transferrin receptor (TFR) overexpressed Lewis lung carcinoma (LLC–luc) cell-bearing mice model. Moreover, the TF-functionalized scaffold displayed a reduced systemic toxicity compared to that of Taxol intravenous injection. Overall, the proposed TF-decorated prodrug NPs could be a promising nanomedicine for intracellular PTX delivery against metastatic lung cancer.

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Effects of various parameters on ultrasonic comminution of coal in water media

Cited by 19 publications

References 20 publications

Preparation of submicron calcite particles by combined wet stirred media milling and ultrasonic treatment

Preparation of submicron calcite particles by combined wet stirred media milling and ultrasonic treatment

Micronization of Hard Coal with the Use of a High-Pressure Water Jet

Engineering Transferrin-Decorated Pullulan-Based Prodrug Nanoparticles for Redox Responsive Paclitaxel Delivery to Metastatic Lung Cancer Cells

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