Effects of vernonia amygdalina fractionate on glutathione reductase and glutathione-S-transferase on alloxan induced diabetes wistar rat

Onyibe, Priscillia Nkem; Edo, Great Iruoghene; Nwosu, Laurine Chikodiri; Özgör, Erkay

doi:10.1016/j.bcab.2021.102118

Cited by 61 publications

(16 citation statements)

References 59 publications

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“…These food products may have been contaminated by biotic or abiotic factors [16], which appear to be one of the most important elements that promote fungus development in food [29]. Also, it was recorded that various species of fungus were extracted from each sample Motor Bike 78% [30]. The Branded [1] stored in open containers was more contaminated than other cultured samples.…”

Section: Discussionmentioning

confidence: 99%

Isolation and Identification of Bacterial and Fungal Spoilage Organisms in Branded and Unbranded Milk; Consumer Perception of Safety Hazard for Milk

Onoharigho

Ighede²,

Akpoghelie³

et al. 2022

Applied Microbiology: Theory ＆ Technology

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Background: This research aims to isolate and identify bacterial and fungal spoilage organisms in branded and unbranded milk, as well as to assess the parameters linked to milk safety risk. A total of 30 samples were collected for laboratory testing. For analysis, the samples were inoculated on several mediums. The bacterial and fungal isolates were identified using Gram staining and biochemical identification methods. Results: According to the findings, Klebsiella spp. and Escherichia coli are the most common bacteria found in isolated organisms from branded and unbranded milk (22.6%). Meanwhile, 8.8% of both Enterococcus faecalis and Streptococcus faecalis were found in the samples. 3.7% of Serratia marcescens and some Streptococcus species were all identified in the samples. At the milk outlets, regularly opening containers to sell milk and predisposing the milk to hand contamination increased the risk of contamination by environmental contaminants. Survey was done with 60 respondents, 37 (61.67%) said they were aware of the health risks associated with milk. Twenty-three people (38.33%) said they knew about diseases linked to drinking contaminated milk. It also discovered that there was no formal food hygiene training for any of the food handlers. However, 11.7% of the workers had advanced training in a variety of fields. Conclusions: The microorganisms associated with milk products’ spoilage in this study are of economical and public health significance. Some strains of A. flavus have been reported to produce potent mycotoxins called ochratoxin that can be harmful to human beings and animals. Cares should be taken on the handling of milk and milk products. And the improved preservation methods should be suggested to enhance the quality of milk products. The findings of the study provide a foundation fordeveloping better milk policies.

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Section: Discussionmentioning

confidence: 99%

Isolation and Identification of Bacterial and Fungal Spoilage Organisms in Branded and Unbranded Milk; Consumer Perception of Safety Hazard for Milk

Onoharigho

Ighede²,

Akpoghelie³

et al. 2022

Applied Microbiology: Theory ＆ Technology

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“…24 The ROS productions have been seen to result to cell damages and inducing the cascades of signaling mechanism which conclusively lead to cellular differentiation, adaptation, proliferation, necrosis or apoptosis. 30,31 It is seen to be highly reactive and vulnerable to free radicals and specifically reactive oxygen species as a result of possessing sulphuric and unsaturated molecules, amino acids such as phenylalanine, mitonin, cysteine, histidine and tryptophan. 19,15 This has helped split the amino acid series, incorporate amino acid chains and also alter amino acids biochemical structures and causes proteolytic changes in protein compounds.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2022

JAPLR

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The main objective of the experiment is aimed to examine the impact of paraquat dichloride on the body weights of adult male Wistar rats as well as in their haematological tissues. The total number of male Wistar rats was 48 and was divided into 4 groups of 12 each. The 1 st group (Test 1) served as control. The other three groups served as experimental groups in which the paraquat dichloride was administered. The experimental groups which are 2 nd group (Test 2), 3 rd group (Test 3) and 4 th group (Test 4) received doses of paraquat dichloride of 10 mg/kg b.wt/per oral/day, 20 mg/kg b.wt/per oral/day and 40 mg/kg b.wt/per oral/ day respectively. The experiment was carried out for a time duration of 42 days. The mean values of body weights, erythrocyte indices, total erythrocyte count (TEC), total leucocyte count (TLC) and Hb concentrations were significantly (P<0.05) decreased in Test 2, 3 and 4 rats, excluding packed cell volume (PCV), which in comparison to the control groups. Outcomes and observations from hematological parameters and bone marrow revealed the toxicity of paraquat dichloride to hematological tissues resulting in anemia and bone marrow hypoplasia which eventually leads to failure of the bone marrow and extensively hematopoietic system of adult male Wistar rats following long term exposure and high concentration.

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“…cane or refined sugars) and early harvest (indicating that the sucrose in honey samples were totally converted into sugars e.g. glucose and fructose) 29,55,56 The sucrose quantity is evaluated with the aim to detect some unsuitable manipulation in honey, and high percentage may be as a result of several adulterations, such as mixing with low-price sweeteners like sugar cane, 57 which means that the sucrose was not completely broken down to glucose and fructose, or feeding the honeybees with syrups of sucrose, resulting to high commercial profit. 58…”

Section: Sugar Content In Honeysmentioning

confidence: 99%

The physicochemical analysis and health benefits of fresh and branded honey produced in delta state, Nigeria

Edo¹,

Onoharigho²,

Emakpor³

et al. 2022

JAPLR

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This research is aimed to investigate and evaluate the physicochemical characteristic of different honey produced in Delta State, Nigeria, to confirm its economical and nutritional quality in comparison with the international standard. The quality of fresh and branded honey samples produced in Delta State was assessed using physicochemical and mineral analysis. Eight fresh honey (FHs) samples and eight branded honey (BHs) samples were collected from the Autonomous Province of Delta State, Nigeria. The tested parameters were pH, free acidity, electrical conductivity, color intensity, moisture, ash, proline, diastase, HMF, invertase, glucose, fructose, sucrose, lipid and mineral content. A qualitative test (Fiehe, Lund and Lugol) was performed to test the purity of honey. Both honey samples displayed good physicochemical properties. The concentration level of sugars was higher in the branded honey in comparison to fresh honey samples. The physicochemical parameters of fresh and branded honey were in concordance with the international standard.

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Effects of vernonia amygdalina fractionate on glutathione reductase and glutathione-S-transferase on alloxan induced diabetes wistar rat

Cited by 61 publications

References 59 publications

Isolation and Identification of Bacterial and Fungal Spoilage Organisms in Branded and Unbranded Milk; Consumer Perception of Safety Hazard for Milk

Isolation and Identification of Bacterial and Fungal Spoilage Organisms in Branded and Unbranded Milk; Consumer Perception of Safety Hazard for Milk

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The physicochemical analysis and health benefits of fresh and branded honey produced in delta state, Nigeria

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