Combined effects of surface roughness and viscosity-pressure dependency on the couple stress squeeze film characteristics of parallel circular plates are presented. On the basis of Christensen's stochastic theory, two types of one-dimensional roughness structures, namely, the radial roughness and azimuthal roughness patterns, are considered and the stochastic modified Reynolds equation for these two types of roughness patterns is derived for Stokes couple stress fluid by taking into account variation of viscosity with pressure. The standard perturbation technique is employed to solve the averaged Reynolds equation and closed form expressions for the mean fluid film pressure, load carrying capacity, and squeeze film time are obtained. It is found that the effects of couple stresses and viscosity-pressure dependency are to increase the load carrying capacity, and squeeze film time for both types of roughness patterns. The effect of azimuthal (radial) roughness pattern is to increase (decrease) these squeeze film characteristics as compared to the corresponding smooth case.