Effects of vitamin D deficiency on left atrial function as evaluated by 2D speckle‐tracking echocardiography

Akhavan-Khaleghi, Niloofar; Hosseinsabet, Ali; Mohseni-Badalabadi, Reza

doi:10.1002/jcu.22548

Cited by 3 publications

(1 citation statement)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5,6 Our knowledge regarding the effects of vitamin D deficiency on the deformation of the myocardium (as an index of the myocardial function) in various cardiac chambers is very limited; what we do know, however, is that vitamin D deficiency does not necessarily lead to the impairment of the functions of the cardiac chambers. 7,8 In one of the two existing studies on the left ventricular (LV) myocardial deformation, only the systolic deformation of the LV myocardium was evaluated in diabetic patients, 7 while myocardial deformation in a diabetic metabolic milieu is different from that in a nondiabetic condition. In the other study, the effects of vitamin D administration were evaluated on the LV systolic deformation without comparing the results with those in a control group.…”

Section: Introductionmentioning

confidence: 99%

Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckle‐tracking echocardiographic study

Omidi

Hosseinsabet

2018

Echocardiography

Self Cite

View full text Add to dashboard Cite

Objectives: Vitamin D deficiency with its high global prevalence is associated with some pathological changes in the myocardium. The aim of our study was to assess the longitudinal deformation of the left ventricular (LV) myocardium in subjects with vitamin D deficiency. Methods:This cross-sectional study recruited 98 consecutive nondiabetic subjects (45 subjects with vitamin D deficiency and 53 subjects without vitamin D deficiency) without significant epicardial coronary artery stenosis. The longitudinal subendocardial deformation indices of the LV myocardium were evaluated with 2D speckletracking echocardiography. Results:The end-systolic strain, the systolic strain rate, and the early and late diastolic strain rates were not statistically significantly different between the subjects with and without vitamin D deficiency. Conclusions:The global longitudinal subendocardial deformations of the LV, including the systolic strain rate and the systolic and diastolic strain rates, as evaluated with 2D speckle-tracking echocardiography were not statistically significantly correlated with the presence or absence of vitamin D deficiency. K E Y W O R D Sleft ventricle, two-dimensional speckle-tracking echocardiography, vitamin D

show abstract

Section: Introductionmentioning

confidence: 99%

Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckle‐tracking echocardiographic study

Omidi

Hosseinsabet

2018

Echocardiography

Self Cite

View full text Add to dashboard Cite

show abstract

Vitamin D deficiency as a seed in a fertile soil: A proposed hypothesis

Davarpasand

2019

Echocardiography

View full text Add to dashboard Cite

In January of 2019, the Echocardiography-a journal of cardiovascular ultrasound and allied techniques published an article entitled as "Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckletracking echocardiographic study". 1 In that research, authors evaluated left ventricular (LV) longitudinal deformation in nondiabetic patients with and without vitamin D deficiency by 2D speckle-tracking echocardiography and found that there was no statistically significant difference between two groups regrading to deformation parameters. Although some of the subjects in two groups suffered from hypertension, the authors alleviated the effect of hypertension on LV myocardial deformation by excluding subjects with increased LV mass. In another recent study, it has been shown that there is no statistically significant difference between left atrial myocardial deformation in aforementioned two groups. 2 However, in diabetic patients, the vitamin D deficiency can lead to decreased deformation of LV myocardium. 3 It can be hypothesized that in the background of a subtle myocardial dysfunction such as diabetes, vitamin D deficiency can lead to decreased myocardial deformation in subjects with normal LV ejection fraction. There are some evidences that support this hypothesis, such as improvement of myocardial deformation in geriatric subjects with vitamin D deficiency and in pediatric subjects with chronic kidney diseases. 4,5 The age and renal diseases can play as a background role that vitamin D deficiency leads to decreased myocardial deformation. It is clear that this hypothesis is different from another hypothesis that proposes epiphenomenon role for vitamin D deficiency. 1. Omidi F, Hosseinsabet A. Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckle-tracking echocardiographic study. Echocardiography. 2019;36:67-73. 2. Akhavan-Khaleghi N, Hosseinsabet A, Mohseni-Badalabadi R. Effects of vitamin D deficiency on left atrial function as evaluated by 2D speckle-tracking echocardiography. J Clin Ultrasound. 2018;46:334-340. 3. Chen Y, Zhao CT, Zhen Z, et al. Association of myocardial dysfunction with vitamin D deficiency in patients with type 2 diabetes mellitus. J Diabetes Complications. 2014;28:286-290. 4. Briguglio M, Gianturco L, Stella D, et al. Correction of hypovitaminosis D improved global longitudinal strain earlier than left ventricular ejection fraction in cardiovascular older adults after orthopaedic surgery. J Geriatr Cardiol. 2018;15:519-522. 5. Deveci M, Aytaç MB, Altun G, et al. Effect of high-dose oral cholecalciferol on cardiac mechanics in children with chronic kidney disease.

show abstract

Evaluation of the Relationship Between Vitamin D Deficiency and Subclinical Cardiac Dysfunction Using 2D/3D Strain Echocardiography in Healthy People

Gerede Uludag,

Aydogan,

Tan

et al. 2024

Kardiologiia

View full text Add to dashboard Cite

Aim. Vitamin D deficiency has a high prevalence in the population and is highly associated with cardiovascular diseases. The aim of this study was to evaluate subclinical left ventricular (LV) function using strain analysis in healthy individuals with vitamin D deficiency.Material and methods. 113 healthy volunteers were enrolled in the study (age, 44.1±7 yrs, 34 male). All volunteers underwent two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography after conventional echocardiographic evaluation. The subjects were divided into two groups according to their vitamin D concentrations. 61 subjects with vitamin D less than 20 ng / ml were included in the vitamin D deficiency group. The baseline clinical characteristics, laboratory measurements, echocardiographic data, including 2D and 3D global longitudinal strain (GLS) values, were compared between the groups.Results. The 2D GLS values of the subjects with vitamin D deficiency were lower (mathematically less negative) than subjects with normal vitamin D (–16.1±3.4 vs –19.3±4.2, p<0.001). Similarly, the 3D GLS results were lower in subjects with vitamin D deficiency (–18.3±5.2 vs –24.1±6.9, p<0.001). A significant correlation was detected between the vitamin D concentrations and the 2D and 3D GLS measurements. (r=0.765 and r=0.628, respectively, p<0.001). Vitamin D was found to be an independent predictor of impaired 2D and 3D LV GLS (p=0.031, p=0.023, respectively).Conclusion. Subclinical LV dysfunction in healthy individuals with vitamin D deficiency was demonstrated by 3D and 2D strain analysis. Due to potential negative effects of vitamin D deficiency on cardiac function, more attention should be paid to healthy individuals with vitamin D deficiency.

show abstract

Effects of vitamin D deficiency on left atrial function as evaluated by 2D speckle‐tracking echocardiography

Abstract: Our findings indicated that LA function, as evaluated by 2DSTE, was not different between subjects with and without vitamin D deficiency after adjustment for the confounding factors.

Cited by 3 publications

References 41 publications

Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckle‐tracking echocardiographic study

Is the longitudinal deformation of the left ventricle affected by vitamin D deficiency in nondiabetics? A 2D speckle‐tracking echocardiographic study

Vitamin D deficiency as a seed in a fertile soil: A proposed hypothesis

Evaluation of the Relationship Between Vitamin D Deficiency and Subclinical Cardiac Dysfunction Using 2D/3D Strain Echocardiography in Healthy People

Contact Info

Product

Resources

About