Effects of vitamin supplementation on microcirculatory disturbance in hemodialysis patients without peripheral arterial disease

Circulating vitamin E, transforming growth factor β1, and the association with renal disease susceptibility in two racial groups with type 2 diabetes

“…However, recent studies have shown that vitamin E supplementation is able to abrogate specific hemodynamic and biochemical abnormalities associated with renal disease in man [34,35]. It is of note in these studies that supplementation achieved concentrations of vitamin E which were similar to those in the Caucasian group in our study.…”

Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram

“…Mean transcutaneous oxygen tension (TcPO 2 ) value is known to be significantly lower in patients receiving hemodialysis than in normal subjects. Oral supplementation with a combination of vitamin C and vitamin E for 6 months to these patients (TcPO 2 <50 mmHg) reportedly improves TcPO 2 values markedly (17). Therefore, in addition to effects on the dermis, ANa might improve stasis or congestion of blood in the eyelid.…”

Antioxidant therapy in hemodialysis patients: a systematic review

“…Four studies reported decreased oxidative stress, [89][90][91][92] two found no effect, 93,94 and one reported a decrease in one biomarker but no change in another. 95 It is interesting to note that a-tocopherol was used in six of the studies, 89,90,[92][93][94][95] with five of these adding vitamin C. 89,90,[93][94][95] Only one of the seven studies used an RCT design with an identical placebo as the control, and this found no effect of an antioxidant combination containing a-tocopherol and vitamin C taken for 8 weeks. 93 There is increasing interest in the use of foods high in antioxidants as dietary antioxidant supplements.…”