In this study, a novel cooling system that combines a vortex tube with an absorption cooler is presented. The system produces cooling effects from both devices. The compressed air enters the vortex tube to produce a cooling effect, and the hot air escaped from the vortex tube is used to drive the absorption cooler. The theoretical model has been built and employed to study the performance of the hybrid cooling system, in terms of the specific cooling load and the coefficient of performance, under the effect of different parameters (feed air pressure, feed air temperature, and cold/hot mass fractions). Further, the hybrid system performance is compared to the performance of the vortex tube alone. The results showed that the cooling capacity of the system increases with an increase of both the feed air temperature and the feed air pressure. The maximum coefficient of performance of the system under current design points is 29.3% greater than the maximum coefficient of performance of the standalone vortex tube.