Effects of Waterpipe Smoke Exposure on Experimentally Induced Chronic Kidney Disease in Mice
Sumaya Beegam,
Suhail Al-Salam,
Nur Elena Zaaba
et al.
Abstract:Tobacco smoking is an independent risk factor in the onset of kidney disease. To date, there have been no reports on the influence of waterpipe smoke (WPS) in experimentally induced chronic kidney disease (CKD) models. We studied the effects and mechanisms of actions of WPS on a mouse model of adenine-induced CKD. Mice fed either a normal diet, or an adenine-added diet and were exposed to either air or WPS (30 min/day and 5 days/week) for four consecutive weeks. Plasma creatinine, urea and indoxyl sulfate incr… Show more
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