“…A total of 13 RCTs (41.9%)[18,33,34,42,45-47,49,54-58] described random sequence generation and 9 (29.0%)[18,33,38,39,47,49,51,54,57] described allocation concealment. With the regard to blinding, 4 RCTs (12.9%)[33,45,47,54] blinded the participants and 14 (45.2%)[18,33,36,37,41,43-45,50-54,57] blinded the data collectors. The average dropout rate of participants was 12%, with 7 RCTs reporting a rate in excess of 20%[18,34,47,49,50,53,57].…”