Objectives: Many athletes utilize herbal medicines to enhance their performance. However, studies comprehensively analyzing the impact of Korean herbal medicine (KHM) on exercise performance enhancement are lacking. This study aimed to explore the basis of animal experimental studies on KHM in improving athletic ability and anti-fatigue effects and derive an evidence-based relationship between exercise and KHM intake.Methods: We conducted a systematic search of articles within the Oriental Medicine Advanced Searching Integrated System (OASIS) database. Animal-controlled experimental studies exploring exercise performance and fatigue recovery effects after administering KHM were selected and analyzed. Data were categorized based on exercise methods and outcomes, examining the effects of different KHM.Results: Through experimental research analysis, the effect of KHM on exercise was focused on muscle strength, cardiopulmonary endurance, and anti-fatigue, among basic components of exercise ability. For example, when administering Allii tuberosi semen and Ginseng Radix to an animal model, remarkable muscle strength enhancements were observed. Administration of Allii tuberosi semen, Ginseng Radix, Cervi Parvum Cornu, Ssanghwa-tang, Kyeongok-go, Yukmijihwang-tang, Jakyak-gamcho-tang, and Sogunjung-tang resulted in cardiovascular endurance improvements. Furthermore, Cervi Parvum Cornu, Ganoderma, Ssanghwa-tang, Dangguibohyul-tang, Ssangbohwan, Bojungikgi-tang, Bojungikgi-tang, Jakyak Gamcho-tang, and Sogunjung-tang were effective for fatigue recovery after exercise. We examined the impact of KHM on muscle strength, cardiovascular endurance, and fatigue recovery during exercise.Conclusions: This systematic review of animal-controlled experimental studies establishes a robust evidence-based relationship between KHM consumption and enhanced athletic abilities, offering valuable insights for athletes exploring natural strategies for performance enhancement.
