Effervescent Rosela Ungu Mencegah Penurunan Nilai SOD dan Mencegah Nekrosis Hepar Tikus Wistar yang Diberi Minyak Jelantah

Maulana, Hafiz Iqbal; Ulilalbab, Arya; Priyanto, Anugerah Dani; Estiasih, Teti

doi:10.21776/ub.jkb.2014.028.02.5

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Based on this, the researcher wants to know the extent to which the eff ect brewed of red rosella calyx can lower LDL of Sprague Dawley rat that has been conditioned hyperlipidemia with giving of waste cooking oil. Waste cooking oil can reduce malondialdehyde (an indicator of oxidative stress) (7) and prevent SOD decrease in wistar rats given waste cooking oil (8) .…”

Section: Introductionsmentioning

confidence: 99%

Brewed of Red Rosella Calyx Powder Prevent Decrease HDL on Sprague dawley Given Waste Cooking Oil

Ulilalbab

Maskanah²

2021

jifi

View full text Add to dashboard Cite

Lipid metabolism disorder is caused by waste cooking oil that is one of the source of exogenous free radicals. Publics know the utilization of red rosella calyx is used as a brew that contains antioxidants. Purpose of this research is to find out the effect of giving brewed red rosella calyx to rat lipid metabolism caused by waste cooking oil on High-density Lipoprotein (HDL) value. This research used 24 male rats which were selected by random sampling and divided into 4 groups: positive control (2 ml kg/BW waste cooking oil given), negative control (without treatment), treatment 1 (2 ml/kg BW waste cooking oil given and giving of 540 mg/kg BW brewed red rosella calyx), and treatment 2 (2 ml/kg BW waste cooking oil given and giving of 810 mg/kg BW brewed red rosella calyx). One-way Analysis of Variance (α = 0.01) and Tukey honestly significant difference test showed that HDL p-value = 0.00. All groups have a significant effect on HDL. The best value is giving of 810 mg/kg BW dose of brewed red rosella calyx (HDL of 57.47 mg/dl). Giving of brewed red rosella calyx dose of 540 mg/kg BW (EC50 = 407.52 bpj) and red rosella calyx dose 810 mg/kg BW (EC50 = 247.82 bpj) can prevent HDL decrease. Red rosella calyx can improve the lipid profile of waste cooking oil treated to Sprague Dawley rats (especially for HDL on this research).

show abstract

Section: Introductionsmentioning

confidence: 99%

Brewed of Red Rosella Calyx Powder Prevent Decrease HDL on Sprague dawley Given Waste Cooking Oil

Ulilalbab

Maskanah²

2021

jifi

View full text Add to dashboard Cite

show abstract

“…Rosella contains many anthocyanins in which 1 gram of rosella contains 56. The antioxidants contained in purple rosella effervescent have been shown to be effective in preventing hepatic necrosis in Wistar rats (Maulana et al 2014) and counteracting free radicals from waste cooking oil (Ulilalbab et al 2012). Further studies are needed whether antioxidant rosella extract can counteract free radicals from exposure to cigarette smoke.…”

Section: Introductionmentioning

confidence: 99%

Purple Rosella (Hibiscus sabdariffa Linn.) Petal Extract Prevents Hepatocyte Degeneration in Wistar Rats Exposed to Cigarette Smoke

Ulilalbab

Wiratmadi

Adriani

2018

FMI

Self Cite

View full text Add to dashboard Cite

Currently, the number of smokers in Indonesia is still high. Cigarette smoke contains free radicals. This study aimed to analyze the effects of purple rosella petal extract on the prevention of hepatocyte degeneration in Wistar rats exposed to cigarette smoke. Twenty male rats were divided into four groups: negative control, positive control, treatment group receiving 270 mg/kg BW purple rosella petal extract, and treatment group receiving 540 mg/kg BW purple rosella calyx extract. Negative control was only given with standard feed. Positive control was given with standard feed and exposed to 2 cigarettes a day. Treatment groups were fed with standard feed and administered with rosella extract in the morning then exposed to 2 cigarettes every day. This study was conducted for 28 days. At the end of the study, hepatocyte degeneration was observed in liver histopathology stained with hematoxilin eosin. The administration of purple rosella petal extracts in the doses of 540 mg/kgBW and 270 mg/kgBW significantly (p<0.05) prevented hepatocyte degeneration. Purple rosella petal extract is able to prevent hepatocyte degeneration in Wistar rats exposed to cigarette smoke.

show abstract

The Effect of Giving Okra (Abelmoschus esculentus L.) Juice on HDL Levels in the Blood Serum of Wistar Strain Rats Fed High-Fat Feed

Alifah

Peniati

Rudyatmi

et al. 2020

IOP Conf. Ser.: Mater. Sci. Eng.

View full text Add to dashboard Cite

Cardiovascular disease is the biggest cause of death in the world with the number of deaths reaching 17.7 million people (31% of the total number of deaths). The main cause of cardiovascular disease is a disturbance in the function of the heart and blood vessels caused by atherosclerosis due to the deposition of cholesterol in artery walls. High Density Lipoprotein (HDL) functions to transport free cholesterol contained in the endothelial peripheral tissue to HDL receptors located in the liver so that it can be processed to be used as bile. Therapy to increase levels of HDL in the blood using okra juice (Abelmoschus esculentus L.) can be done in rats that have been given high-fat feed. The purpose of this study was to determine the effect of okra juice (Abelmoschus esculentus L.) on HDL levels in rats fed high fat. The study was conducted with giving okra juice (Abelmoschus esculentus L) with dosage difference of 1500 mg/kg bw, 3000 mg/kg bw and 6000 mg/kg bw. The research design used was complete random design with post-test randomized group design with a number of replications 5. Testing of HDL levels was carried out by the CHOD-PAP (Cholesterol Oxidase Para Aminophenazone) method. The research data were analyzed using one-way Anova followed by LSD tests. The results of the study giving okra juice (Abelmoschus esculentus L.) to HDL levels by induction of high-fat feed at a dose of 6000 mg / kg body weight were significantly different from lower dosage. Conclusion, okra juice (Abelmoscus esculentus L.) has a positive effect on increasing HDL levels..

show abstract

Effervescent Rosela Ungu Mencegah Penurunan Nilai SOD dan Mencegah Nekrosis Hepar Tikus Wistar yang Diberi Minyak Jelantah

Cited by 3 publications

References 0 publications

Brewed of Red Rosella Calyx Powder Prevent Decrease HDL on Sprague dawley Given Waste Cooking Oil

Brewed of Red Rosella Calyx Powder Prevent Decrease HDL on Sprague dawley Given Waste Cooking Oil

Purple Rosella (Hibiscus sabdariffa Linn.) Petal Extract Prevents Hepatocyte Degeneration in Wistar Rats Exposed to Cigarette Smoke

The Effect of Giving Okra (Abelmoschus esculentus L.) Juice on HDL Levels in the Blood Serum of Wistar Strain Rats Fed High-Fat Feed

Contact Info

Product

Resources

About