“…Then glyphosate induces the suppression of protein synthesis and secondary metabolites, e.g., flavonoids, lignin inducing cell death (Cao et al 2012;Sviridov et al 2015;Fu et al 2017). The shikimate pathway is found only in microorganisms and plants, never in animals and humans (Samsel and Seneff 2013;Ovono et al 2019), because they do not make their own aromatic amino acids (phenylalanine, tyrosine, and tryptophan), but obtain them from food (Padgette et al 1995) There are two classes of EPSPS: class I are naturally sensitive to glyphosate and occur in plants and many Gram-negative bacteria (e.g., Escherichia coli and Salmonella typhimurium), while class II EPSPS are involved in resistance to glyphosate and are found only in bacteria, including Agrobacterium sp. strain CP4 and Pseudomonas sp.…”