Effets de l’hydroxyzine sur l’acceptation du masque à l’induction de l’enfant

Trifa, Mehdi; Khalifa, S. Ben; Gargouri, Faouzi; Kaouech, N.; M, Friaa

doi:10.1016/j.annfar.2009.10.019

Cited by 6 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oral promethazine is administered in a dose of 0,3mgkg -1 18 . Compared to placebo, administration of oral hydroxyzine 1mgkg -1 and promethazine 1¾ hour prior to induction respectively resulted in a significant (p<0,05) better tolerance of inhalational induction 18,100 . Promethazine was equally effective compared to oral midazolam 0,5mgkg -1 regarding stress reduction at parental separation and induction 18 .…”

Section: Advantages-disadvantagesmentioning

confidence: 96%

Pharmacological strategies to reduce perioperative anxiety in children – a narrative review

Knaeps,

Van de Putte,

Van de Velde

2023

Acta Anaest Belg

View full text Add to dashboard Cite

Preoperative anxiety is common among children, resulting in negative postoperative behavior and increased postoperative pain. This review focuses on the practical use, safety, and efficacy of pharmacological strategies to reduce perioperative anxiety in children. The PubMed® database was searched using MeSH terms: ((care, preoperative) AND (children) AND (anti-anxiety drugs); (medication, preanesthetic) AND (child, preschool). An in-dept assessment was performed after which 85 articles were retrieved. Benzodiazepines (midazolam, diazepam), zolpidem, melatonin, opioids (fentanyl, butorphanol), alpha-2-adrenergic receptor agonists (clonidine, dexmedetomidine), ketamine and antihistamines (hydroxyzine, promethazine) were reviewed. Their pharmacological properties, routes of administration, doses, efficacy and (dis)advantages are discussed in this review. Based upon the results of our review, some suggestions can be made. Oral midazolam, oral clonidine, intranasally dexmedetomidine and the combination of oral ketamine and midazolam are recommendable products. Some other products like oral diazepam, butorphanol, ketamine intranasal s-ketamine + midazolam and hydroxyzine can be considered because of their proper safety profile and benefits. Further research should focus on patient selection for specific pharmacological and non-pharmacological interventions to achieve a tailored approach. Standardized assessment of anxiety, clinical significancy and feasibility should be included in the objectives of these studies.

show abstract

Section: Advantages-disadvantagesmentioning

confidence: 96%