A. L. Cochrane's Effectiveness and Efficiency frequently appears as a key reference in debates over, and a justification for, contemporary evidence-based medicine. Cochrane's concern in this text with the equality of care as the ultimate rationale for why effectiveness and efficiency of cure are needed has, however, largely disappeared from debate. In this article, we reconsider Cochrane's approach through the use of case studies of plural forms of medicine in the Czech Republic, namely traditional Chinese medicine, homeopathy and spa care. In addition to bringing equality back into the picture, we also identify four expansions to Cochrane's original vision arising from the difficulties of separating cure from care; the overlap between prevention and cure; the complex actions of some multifaceted therapies; and recent reconceptualisations of the placebo effect. In conclusion, we suggest that instead of the widely used strictly vertical "evidence pyramid", a descriptor of the horizontal and additive ordering of evidence might be more appropriate. We also argue that in healthcare systems characterised by a multiplicity of approaches, if we want to truly benefit from this heterogeneity, we must take seriously each medical tradition's approaches to prevention, cure, care, as well as efficiency, efficacy and equality.Keywords: complementary and alternative medicine, Central and Eastern Europe, evidencebased medicine, equity, fairness, health policy, ethnography It is difficult to overestimate the wide-scale impact of A. L. Cochrane's 1971 assessment of the British National Health Service, Effectiveness and efficiency: random reflections on health services. Indeed, Cochrane's strong support of Random Clinical Trials (RCTs) as the most reliable method of data generation in assessing the effectiveness of treatment has become part of a revolution in international healthcare standards. Cochrane's legacy is exemplified by the Cochrane Collaboration, an international forum for medical advice, which focuses on "transform[ing] the way health decisions are made" (Cochrane, n.d.). However, as Askheim et al.(2017) note, contemporary advocates of improving healthcare efficiency tend to pick and choose aspects of Cochrane's position that suit the agendas of RCT-driven treatments. In this article, we take up Askheim and co-authors' call for considering more broadly Cochrane's approach to medical care as a tripartite structure, involving not only effectiveness and efficiency but also equality. We revisit these issues, however, by means of not only conceptual analysis, akin to Askheim et al. (2017), but through the use of empirical case studies of plural forms of medical care in the Czech Republic. Our intention is not only to recover Cochrane's