Phonoctonus lutescens which is a predator of Dysdercus voëlkeri (Schmidt, 1932) is present in cotton fields at the same time as its prey, D. voëlkeri. The objective of this study was to see which of the biological control or chemical control programs spares and maintains the potentially beneficial insects, especially P. lutescens. This study was conducted at three sites: Farako Bâ site located in the southern Sudanian zone and has geographical coordinates between 04˚20' West and 11˚06' North. The site of Kombissiri with 12'04'' North and 1'20'' West as geographical coordinates. The site of Kouaré with the following coordinates: 11'56'' North and 0'17'' East. The design was a 2000 m 2 paired trial subdivided into 3 subplots of 640 m 2 on the three sites. The sample area is repeated 4 times in each plot. All data were subjected to analysis of variance (ANOVA) using SPSS software (version 22.0; SPSS Inc., Chicago, IL, Usa). When significance occurred, means were separated by Bonferroni test (p < 0.05). All data were presented as the mean ± standard errors with 3 replications. For insect pests, conventional cotton was more affected by whitefly with 0.42 ± 1.10 and organic cotton by jassids with 0.75 ± 1.66 at Farako bâ. The untreated plot was significantly less infested at Kombissiri with 0.25 ± 1.38 Dysdercus voëlkeri than at the other sites. In Fada, the organic cotton was more infested by whitefly larvae and jassid flies, with respectively 0.73 ± 2.25 and 0.22 ± 0.54 plants attacked on average.