Efficacité sur la croissance et tolérance d’une préparation pour nourrissons à base de protéines de riz hydrolysées

Girardet, J.-P.; Rivero, Montserrat; Orbegozo, J.M.Romeo; David, T.; Boulanger, S.; Vaux, A. Moisson de; Johnston, S. D.; Marin, V.

doi:10.1016/j.arcped.2012.12.002

Cited by 9 publications

(4 citation statements)

References 11 publications

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“…It is reassuring that our data demonstrated an average weight gain per day of 35.0 ± 3.4 g and an average length gain per day of 0.13 ± 0.01 cm, both within the WHO 2006 recommendations for optimum growth for infants 0-24 months of age [24]. Other studies have shown similar findings in terms of adequate growth in both healthy infants [2,27] as well as infants with CMA [33][34][35][36][37][38][39] while being fed a HRF. More recently, Nieto-Garcia et al conducted a study on the use of a hydrolyzed rice formula over a 12-month period.…”

Section: Discussionsupporting

confidence: 84%

Tolerance of Infants Fed a Hydrolyzed Rice Infant Formula with 2′-Fucosyllactose (2′-FL) Human Milk Oligosaccharide (HMO)

Ramirez-Farias,

Oliver,

Schlezinger

et al. 2024

Nutrients

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Background: The purpose of this research was to assess the growth, tolerance, and compliance outcomes associated with the consumption of a hydrolyzed rice infant formula (HRF) enriched with 2′-Fucosyllactose (2′-FL) a Human Milk Oligosaccharide (HMO), and nucleotides in an intended population of infants. Methods: This was a non-randomized single-group, multicenter study. The study formula was a hypoallergenic HRF with 2′-FL, Docosahexaenoic acid (DHA), Arachidonic acid (ARA), and nucleotides. Infants 0–90 days of age who were formula fed and experiencing persistent feeding intolerance symptoms, symptoms of suspected food protein (milk and/or soy) allergy, or other conditions where an extensively hydrolyzed infant formula was deemed an appropriate feeding option were recruited by pediatricians from their local populations. The primary outcome was maintenance of weight-for-age z-score. Weight, length, head circumference, formula intake, tolerance measures, clinical symptoms and questionnaires were collected. Thirty-three infants were enrolled, and 27 completed the study, on study product. Results: Weight-for-age z-scores of infants showed a statistically significant improvement from Visit 1 to Visit 4 (p = 0.0331). There was an adequate daily volume intake of 762 ± 28 mL/day, average daily number of stools of 2.1 ± 0.3, and mean rank stool consistency of 2.38 ± 0.18. After 28 days of switching to a HRF, 86.8 ± 5.9% of the symptoms resolved or got better by Visit 4 as reported by parents. Conclusions: HRF with 2′-FL HMO was safe, well tolerated, and supported weight gain in infants with suspected cow’s milk allergy or persistent feeding intolerance.

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Section: Discussionsupporting

confidence: 84%

Tolerance of Infants Fed a Hydrolyzed Rice Infant Formula with 2′-Fucosyllactose (2′-FL) Human Milk Oligosaccharide (HMO)

Ramirez-Farias,

Oliver,

Schlezinger

et al. 2024

Nutrients

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“…No data are available for infants breastfed by vegan mothers. In infants not breastfed following a vegan diet, protein malnutrition may occur [ 20 ], hence a rice protein-based infant formula supplemented with lysine, threonine, and tryptophan or a soy-based infant formula fortified with methionine is needed to ensure a normal growth [ 21 ]. Infants fed with soy-isolate drink, whether or not methionine supplemented, were thought to have similar growth rate compared to infants fed with cow’s milk formula [ 22 ].…”

Section: Resultsmentioning

confidence: 99%

Vegetarian and Vegan Weaning of the Infant: How Common and How Evidence-Based? A Population-Based Survey and Narrative Review

Martire

Panza

Farella

et al. 2020

IJERPH

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Background: Vegetarian and vegan weaning have increasing popularity among parents and families. However, if not correctly managed, they may lead to wrong feeding regimens, causing severe nutritional deficiencies requiring specific nutritional support or even the need for hospitalization. Aim: To assess the prevalence of vegetarian and vegan weaning among Italian families and to provide an up-to-date narrative review of supporting evidence. Materials and methods: We investigated 360 Italian families using a 40-item questionnaire. The narrative review was conducted searching scientific databases for articles reporting on vegetarian and vegan weaning. Results: 8.6% of mothers follow an alternative feeding regimen and 9.2% of infants were weaned according to a vegetarian or vegan diet. The breastfeeding duration was longer in vegetarian/vegan infants (15.8 vs. 9.7 months; p < 0.0001). Almost half of parents (45.2%) claim that their pediatrician was unable to provide sufficient information and adequate indications regarding unconventional weaning and 77.4% of parents reported the pediatrician’s resistance towards alternative weaning methods. Nine studies were suitable for the review process. The vast majority of authors agree on the fact that vegetarian and vegan weaning may cause severe nutritional deficiencies, whose detrimental effects are particularly significant in the early stages of life. Discussion and conclusion: Our results show that alternative weaning methods are followed by a significant number of families; in half of the cases, the family pediatrician was not perceived as an appropriate guide in this delicate process. To date, consistent findings to support both the safety and feasibility of alternative weaning methods are still lacking. Since the risk of nutritional deficiencies in the early stages of life is high, pediatricians have a pivotal role in guiding parents and advising them on the most appropriate and complete diet regimen during childhood. Efforts should be made to enhance nutritional understanding among pediatricians as an unsupervised vegetarian or vegan diet can cause severe nutritional deficiencies with possible detrimental long-term effects.

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“…The Z-scores for weight, height, and BMI varied between +1.1 and −0.5 SD according to the WHO standards. Formula acceptance and tolerance were both good [65]. Last, a prospective trial assessed clinical tolerance of eRHF [30].…”

Section: Rice Hydrolised Formulaementioning

confidence: 99%

Cow’s milk allergy: towards an update of DRACMA guidelines

Fiocchi

Dahda

Dupont

et al. 2016

World Allergy Organization Journal

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BackgroundIn 2010, the diagnosis and treatment of IgE-mediated CMA were systematized in a GRADE guideline.Objectives & methodsAfter 6 years, the state of the knowledge in diagnosis and treatment of CMA has largely evolved. We summarize here the main advances, and exemplify indicating some specific points: studies aimed at better knowledge of the effects of breastfeeding and the production of new special formulae intended for the treatment of CMA. The literature (PubMed/MEDLINE) was searched using the following algorithms: (1) [milk allergy] AND diagnosis; (2) [milk allergy] AND [formul*] OR [breast*], setting the search engine [6-years] time and [human] limits. The authors drew on their collective clinical experience to restrict retrieved studies to those of relevance to a pediatric allergy practice.ResultsSeveral clinical studies did address the possibility to diagnose CMA using new tools in vitro and in vivo, or to diagnose it without any evaluation of sensitization. Some studies also addressed the clinical role of formulae based on milk hydrolysates, soy, or rice hydrolysates in the treatment of CMA. Many studies have elucidated the effects of selective nutrients in breastfed infants on their immunologic and neurologic characteristics.ConclusionsEvidence-based diagnostic criteria should be identified for non-IgE-mediated CMA. Debate is ongoing about the best substitute for infants with CMA. In particular, Hydrolyzed Rice Formulae have been widely assessed in the last six years. In the substitute choice, clinicians should be aware of recent studies that can modify the interpretation of the current recommendations. New systematic reviews and metanalyses are needed to confirm or modify the current DRACMA recommendations.

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Efficacité sur la croissance et tolérance d’une préparation pour nourrissons à base de protéines de riz hydrolysées

Cited by 9 publications

References 11 publications

Tolerance of Infants Fed a Hydrolyzed Rice Infant Formula with 2′-Fucosyllactose (2′-FL) Human Milk Oligosaccharide (HMO)

Tolerance of Infants Fed a Hydrolyzed Rice Infant Formula with 2′-Fucosyllactose (2′-FL) Human Milk Oligosaccharide (HMO)

Vegetarian and Vegan Weaning of the Infant: How Common and How Evidence-Based? A Population-Based Survey and Narrative Review

Cow’s milk allergy: towards an update of DRACMA guidelines

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