Efficacy and Adverse Effects of Q-Switched Ruby Laser on Solar Lentigines

A Prospective Randomized Controlled Study of Oral Tranexamic Acid for Preventing Postinflammatory Hyperpigmentation After Q-Switched Ruby Laser

“…QSRL is effective for treating a variety of hyperpigmented lesions, even in participants with dark skin, 1 although PIH is a frequent adverse effect. Our results showing negative effects of oral TA against post‐QSRL PIH suggest that PIH should be prevented using other bleaching agents such as hydroquinone as a representative suppressor of melanin production and tretinoin as a representative accelerator of melanin discharge.…”

“…Postinflammatory hyperpigmentation (PIH) is the most frequently observed complication associated with the use of Q‐switched lasers for treating hyperpigmented lesions in Asians 1 . Fitzpatrick skin type affects the degree and frequency of PIH.…”

“…Fitzpatrick skin type affects the degree and frequency of PIH. In particular, patients with melasma and darker skin should be monitored for PIH 1 . Although a variety of treatments for PIH have been reported, a reliable method of prevention of PIH has not been established.…”

Laser Eradication of Pigmented Lesions: A Review

“…In 2002, Rashid and colleagues evaluated a quasi‐continuous Nd:YAG (532 nm) in 6 patients with solar lentigines, all of whom had greater than 50% improvement 15 . The QSRL was further evaluated by Sadighha and colleagues in 2008 in 89 patients, all of whom had complete clearance of lesions after one to two treatments 16 …”

Rejuvenation of the Aging Chest: A Review and Our Experience

“…Adverse events include pain, crusting, bleeding, bullae, hyperpigmentation, hypopigmentation, and scarring 53,60 . The incidence of PIH and hypopigmentation is greater in darker skin types 60 .…”