Efficacy and safety of a fixed-dose combination of D-norpseudoephedrine, triiodothyronine, atropine, aloin, and diazepam in obese patients

Abstract

Data suggest that the FDC is effective and well tolerated for the short-term therapy of overweight and obesity in Mexican patients. .

Aloe vera (L.) Webb.: Natural Sources of Antioxidants – A Review

“…Long-term use of anthraquinones may result in intestine inflammation, it may prolong menstrual bleeding and cause difficulties in the absorption of nutrients [24]. Due to aloin, the daily intake of aloe juice should not exceed 30–40 mL, because excessive consumption may not only have a strong laxative effect but also toxic effects [54]. Apart from that, aloin inhibits lipid peroxidation in the cerebral cortex by inactivation of Fe(II)-dependent ascorbate.…”

From Aloe vera Leaf Waste to the Extracts with Biological Potential: Optimization of the Extractions, Physicochemical Characterization, and Biological Activities

“…Aloe has shown antitumor, antimicrobial, antiviral, anti-inflammatory, antioxidant, hypocholesterolemic, hypoglycemic, antiulcerogenic, immunomodulatory, analgesic, dermal protection, wound healing, burn healing, and frostbite healing activities [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. Aloe is widely used as an active ingredient in laxative and antiobesity preparations and as a moisturizer, emollient, or wound-healing agent in pharmaceuticals, sunscreen, and other cosmetic formulations [ 1 , 8 , 9 ]. It has cathartic properties through action on the colon and indirectly stimulates peristalsis via induction of electrolytes and water secretion in the intestinal lumen, inhibition of their reabsorption from the large intestine, and consequently the increase in intestinal volume and filling pressure [ 1 , 8 ].…”

“…Aloe is widely used as an active ingredient in laxative and antiobesity preparations and as a moisturizer, emollient, or wound-healing agent in pharmaceuticals, sunscreen, and other cosmetic formulations [ 1 , 8 , 9 ]. It has cathartic properties through action on the colon and indirectly stimulates peristalsis via induction of electrolytes and water secretion in the intestinal lumen, inhibition of their reabsorption from the large intestine, and consequently the increase in intestinal volume and filling pressure [ 1 , 8 ]. Carboxypeptidase, a serine carboxypeptidase enzyme, is a primary antithermic agent that showed analgesic activity and dermoprotectant activity against burns [ 1 , 4 ].…”