Efficacy and Safety of a Hyaluronic Acid Filler to Correct Aesthetically Detracting or Deficient Features of the Asian Nose: A Prospective, Open-Label, Long-Term Study

Abstract

BackgroundThere is increasing interest among patients and plastic surgeons for alternatives to rhinoplasty, a common surgical procedure performed in Asia.ObjectivesTo evaluate the safety, efficacy, and longevity of a hyaluronic acid filler in the correction of aesthetically detracting or deficient features of the Asian nose.MethodsTwenty-nine carefully screened Asian patients had their noses corrected with the study filler (Juvéderm VOLUMA [Allergan plc, Dublin, Ireland] with lidocaine injectable gel), reflecting individualized treatment goals and utilizing a standardized injection procedure, and were followed for over 12 months.ResultsA clinically meaningful correction (≥1 grade improvement on the Assessment of Aesthetic Improvement Scale) was achieved in 27 (93.1%) patients at the first follow-up visit. This was maintained in 28 (96.6%) patients at the final visit, based on the independent assessments of a central non-injecting physician and the patients. At this final visit, 23 (79.3%) patients were satisfied or very satisfied with the study filler and 25 (86.2%) would recommend it to others. In this small series of patients, there were no serious adverse events (AEs), with all treatment-related AEs being mild to moderate, transient injection site reactions, unrelated to the study filler.ConclusionsUsing specific eligibility criteria, individualized treatment goals, and a standardized injection procedure, the study filler corrected aesthetically detracting or deficient features of the Asian nose, with the therapeutic effects lasting for over 12 months, consistent with a high degree of patient satisfaction. This study supports the safety and efficacy of this HA filler for specific nose augmentation procedures in selected Asian patients.Level of Evidence: 3 Therapeutic

Non-surgical minimally invasive rhinoplasty: tips and tricks from the perspective of a dermatologist

“…For instance, Asians usually have a flat nose with a wide alar base, wide nasal tip, and retracted columella, whereas Caucasians have a prominent dorsum and nasal tip. Therefore, the procedure varies depending on patients' expectations (16). Here we report our experience with filler rhinoplasty in 35 Turkish patients and detail how we performed it.…”

Safety and early satisfaction assessment of patients seeking nonsurgical rhinoplasty with filler

“…Isolated reports of tip necrosis have been published in the literature following the use of fillers of all types, and it has been documented as a rare complication of surgical rhinoplasty. [ 4 ] The mechanism behind this is assumed to be compression, occlusion, and/or embolization of these vessels. These events are clearly not unique to the nasal vasculature, with similar reports seen following administration of fillers in the forehead, glabellar, temple, and the nasolabial region.…”

“…Surgical rhinoplasty, “nose job”, according to ASAPS statistics (2016), is the sixth of the most requested procedures;[ 2 ] however, the so-called nonsurgical rhinoplasty with fillers in the last few years has shown to be an effective alternative for patients seeking only an aesthetic improvement of the nose. [ 4 ]…”

“…Several articles regarding Asian nose augmentation with fillers have been published;[ 3 4 5 ] however, in Western countries also, the so-called “nonsurgical rhinoplasty,” often called “rhinofiller,” is often performed although with different end points.…”

Injizierbare Füllmaterialien – Update und Zukunftsperspektive

“…Die Verfärbung entsteht hierbei durch eine Brechung des Lichtes an den Hyaloronsäure-Partikeln und wird als Tyndall-Effekt bezeichnet. In seltenen Fällen wurden Hautnekrosen nach der Injektion beschrieben [13]. Bei Applikation im Gesichtsbereich kann eine irrtümliche Injektion in ein Gefäß eine Embolisierung der A. retinae und folglich einen partiellen oder kompletten Gesichtsfeldausfall nach sich ziehen [14].…”