Efficacy and safety of acupuncture for polycystic ovary syndrome: An overview of systematic reviews

Xiao, Zhiyong; Yin, Zihan; Zheng, Yu; Li, Jiajia; Xiao, Yan-Qun; Zhou, Ruhong; Li, Juan; Yang, Jie; Liang, Fanrong

doi:10.1016/j.joim.2022.12.002

Cited by 5 publications

(1 citation statement)

References 36 publications

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“…[19] Numerous meta-analyses have confirmed that TCM therapies are superior to western medicines and surgical treatments with regard to cycle ovulation rate, pregnancy rate, and adverse effects. [20][21][22][23][24][25][26] Numerous clinical studies and experimental data above are conclusive in demonstrating that TCM is proficient in regulating endocrine and metabolic imbalances prevalent in PCOS with the characteristics of multi-components, multitargets, and multi-pathways, and that the drug safety is high. [27][28][29][30][31][32] However, TCM therapies are diverse and have varying efficacies.…”

Section: Introductionmentioning

confidence: 99%

Combined traditional Chinese medicine therapy for the treatment of infertility with polycystic ovary syndrome: A network meta-analysis of randomized controlled trials

Deng,

Zhou,

Wei

et al. 2024

Medicine

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Background: Polycystic ovary syndrome (PCOS) infertility has attracted great attention from researchers due to its high incidence. Numerous studies have shown that Chinese medicine is effective in treating this disease, but there is a wide variety of Chinese medicine therapies available, and there is a lack of comparative evaluation of the efficacy of various Chinese medicine combination therapies in the clinic, which requires further in-depth exploration. This study aims to evaluate the efficacy of a combined traditional Chinese medicine (TCM) therapy for the treatment of infertility with PCOS using network meta-analysis (NMA). Methods: In PubMed, web of Science, Cochrane Library, Embase, China Knowledge Network, Wanfang Data, VIP Database, China Biomedical Literature Database (SinoMed) databases, searchs were conducted for information about the randomized controlled trials (RCTs) of combined TCM therapy for the treatment of infertility with PCOS. Quality evaluation was performed using the Cochrane 5.3 risk of bias assessment tool, and NMA using Stata 16.0. Results: This study comprised 28 RCTs using 8 combined TCM therapies in total. The results of the NMA showed that moxibustion + herbal, fire acupuncture + herbal, acupuncture + herbal, electroacupuncture + herbal, and acupoint application + herbal improved the clinical pregnancy rate better than acupuncture, herbal, and western medicines monotherapy (P < .05). Additionally, ear point pressure + herbal enema + herbal, acupuncture and moxibustion + herbal, fire acupuncture + herbal, and acupuncture + herbal improved the ovulation rate better than acupuncture, herbal, and western medicines monotherapy (P < .05). Moxibustion + herbal, fire acupuncture + herbal, and acupuncture + herbal are the 3 most effective therapies for improving the clinical pregnancy rate. Fire acupuncture + herbal, acupuncture + herbal, and ear point pressure + herbal enema + herbal are the 3 most effective therapies for improving the ovulation rate. Conclusion: The combined TCM therapy demonstrated better efficacy for the treatment of infertility with PCOS compared to acupuncture, herbal, and western medicines monotherapy. However, the optimal treatment therapy varied depending on the outcome indicators. Further large sample, high-quality, and standardized RCTs are needed to verify these findings.

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