Efficacy and safety of dacron patch in surgical treatment of congenital disease by echocardiography

Deng, Mingbin; Yang, Qian

doi:10.1016/j.jiph.2019.08.009

Cited by 5 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One is the auto pericardial patch, with a good histocompatibility and tissue activity, but it is inaccessible and weak. The other one is the Dacron patch, which has a thin texture and a strong tension and elasticity, and is prone to anastomotic deformation, thrombosis, embolism, hemolysis and infection after repair [14].…”

Section: Current Reports and Actual Evidencementioning

confidence: 99%

Surgical Atrial Septal Patch Endocarditis in a Patient with a Complete Corrected Atrioventricular Canal Defect: A Case Report and Review of the Literature

Șerban

Achim²,

Gavan³

et al. 2023

Diagnostics

View full text Add to dashboard Cite

Infective endocarditis (IE) is common in patients with corrected congenital heart disease (CHD) with a residual lesion, but is rarely found on surgical patches used to close atrial septal defects (ASDs). This is also reflected in the current guidelines that do not recommend antibiotic therapy for patients with a repaired ASD with no residual shunt six months after closure (percutaneous or surgical). However, the situation could be different in the case of mitral valve endocarditis, which causes leaflet disruption with severe mitral insufficiency and could seed the surgical patch. We present herein a 40-year-old male patient with a past medical history of a complete surgically corrected atrioventricular canal defect performed in childhood who presented with fever, dyspnea and severe abdominal pain. Transthoracic and transesophageal echocardiography (TTE and TEE) revealed vegetation at the level of the mitral valve and the interatrial septum. The CT scan confirmed ASD patch endocarditis and multiple septic emboli, guiding the therapeutic management. An accurate evaluation of cardiac structures should be mandatory when a systemic infection is detected in CHD patients, even if the defects were surgically corrected, because the detection and eradication of such infectious foci as well as a surgical reintervention are particularly difficult to achieve in this subpopulation.

show abstract

Section: Current Reports and Actual Evidencementioning

confidence: 99%

Surgical Atrial Septal Patch Endocarditis in a Patient with a Complete Corrected Atrioventricular Canal Defect: A Case Report and Review of the Literature

Șerban

Achim²,

Gavan³

et al. 2023

Diagnostics

View full text Add to dashboard Cite

show abstract

A Prevascularized Polyurethane‐Reinforced Fibrin Patch Improves Regenerative Remodeling in a Rat Right Ventricle Replacement Model

Zheng

Jarrell

Robinson

et al. 2021

Adv Healthcare Materials

View full text Add to dashboard Cite

Congenital heart defects (CHDs) affect 1 in 120 newborns in the United States. Surgical repair of structural heart defects often leads to arrhythmia and increased risk of heart failure. The laboratory has previously developed an acellular fibrin patch reinforced with a biodegradable poly(ether ester urethane) urea mesh that result in improved heart function when tested in a rat right ventricle wall replacement model compared to fixed pericardium. However, this patch does not drive significant neotissue formation. The patch materials are modified here and this patch is prevascularized with human umbilical vein endothelial cells and c-Kit + human amniotic fluid stem cells. Rudimentary capillary-like networks form in the fibrin after culture of cell-encapsulated patches for 3 d in vitro. Prevascularized patches and noncell loaded patch controls are implanted onto full-thickness heart wall defects created in the right ventricle of athymic nude rats. Two months after surgery, defect repair with prevascularized patches results in improved heart function and the patched heart area exhibited greater vascularization and muscularization, less fibrosis, and increased M2 macrophage infiltration compared to acellular patches.

show abstract

An in vitro characterization of a PCL-fibrin scaffold for myocardial repair

Jarrell,

Jacot

2023

Materials Today Communications

View full text Add to dashboard Cite

Efficacy and safety of dacron patch in surgical treatment of congenital disease by echocardiography

Cited by 5 publications

References 15 publications

Surgical Atrial Septal Patch Endocarditis in a Patient with a Complete Corrected Atrioventricular Canal Defect: A Case Report and Review of the Literature

Surgical Atrial Septal Patch Endocarditis in a Patient with a Complete Corrected Atrioventricular Canal Defect: A Case Report and Review of the Literature

A Prevascularized Polyurethane‐Reinforced Fibrin Patch Improves Regenerative Remodeling in a Rat Right Ventricle Replacement Model

An in vitro characterization of a PCL-fibrin scaffold for myocardial repair

Contact Info

Product

Resources

About