Efficacy and safety of different anti-osteoporotic drugs for the spinal fusion surgery: A network meta-analysis

Abstract

Rehabilitation of lower limb amputation in developing countries is quite challenging. Though there are basic to highly advanced prostheses available in India, the set-up is still facing difficulties in developing countries. Prosthetic management is difficult due to lack of availability of prostheses and reduced affordability among low income populations. In this review we highlighted the lower limb amputation and prosthetic rehabilitation status in India. Currently, India is advancing well in the rehabilitation field, but further studies are required to provide more evidence and recommendation.

The influence of osteoporosis on mechanical complications in lumbar fusion surgery: a systematic review

“…Unfortunately, we found relatively limited and inconclusive data regarding a direct association between bone density and fusion. One study observed that fusion took significantly longer in osteoporotic patients [ 44 ], which is consistent with findings reported by meta-analyses of randomized controlled trial data showing osteoporosis treatment improves fusion rates after lumbar instrumentation [ 82 , 83 ]. Liu et al [ 84 ] published the only study in our review using micro-CT. Ex-vivo analysis of spinous process specimens obtained during index surgery revealed higher trabecular number and lower trabecular separation with greater bone surface/total volume (BS/TV) among patients ultimately achieving solid fusion.…”