Efficacy and safety of dorsal penile nerve block before collagenase of clostridium histolyticum injections in peyronie's disease patients: Results from a prospective pilot study

Abstract

Peyronie's disease (PD) is an acquired pathology characterized by the formation of fibrous plaques in the context of the tunica albuginea of the penis, with consequent development of penile deformities (Al-Thakafi & Al-Hathal, 2016). Although the epidemiological data are limited and inconsistent, different studies described an incidence of up to 5% in the general male population (La Pera et al., 2001; Lindsay et al., 1991), with peaks of up to 20.3% in selected subgroups (Arafa, Eid, El-Badry, Ezz-Eldine, & Shamloul, 2007). It affects males of all ages, being more prevalent in middle-advanced age (Schwarzer et al., 2001), but presenting a more aggressive course in younger patients (Taylor & Levine, 2007). It was related to multiple risk factors, being repeated micro-trauma during sexual intercourse the most accredited etiopathogenic theory (Bjekic, Vlajinac, Sipetic, & Marinkovic, 2006; Kadioglu et al., 2002). The natural history of PD is generally subdivided into two successive stages: one acute or inflammatory, with variable duration, followed by another chronic or stable. The acute phase is characterized by pain with erections and the presence of an inflammatory plaque that causes the associated malformations (curvature, shortening or narrowing). In the chronic stage, the inflammation decreases, pain

Pudendal nerve block decreases narcotic requirements and time spent in post-anesthesia care units in patients undergoing primary inflatable penile prosthesis implantation

“…Given the magnitude of the opioid epidemic, efforts to minimize narcotic usage in the post-operative setting has become increasingly important, with nerve blocks becoming increasingly utilized in urologic procedures [25]. For IPP implantation, dorsal penile nerve blocks have been previously shown to provide reductions in pain in the immediate post-operative period, with no differences in narcotic usage between patients receiving the block and those in the placebo group [10].…”

Voice Assistants as Consultants for Male Patients with Sexual Dysfunction: A Reliable Option?

“…ED [14][15][16][17][18][19][20], PE [21], PD [22][23][24][25][26][27][28][29][30], male infertility [31,32], genital aesthetic concerns [33][34][35][36][37], as well as several other conditions [38][39][40][41][42][43][44][45] can significantly impact the sexual health of male patients. When this happens, worries and doubts often lead patients to independently search for information on the Internet with every available tool [1,2].…”