Efficacy and Safety of Enhanced Recovery After Surgery Pathway in Minimally Invasive Colorectal Cancer Surgery: A Systemic Review and Meta-Analysis

Li, Niu; Liu, Yanbiao; Chen, Huijuan; Sun, Yefei

doi:10.1089/lap.2022.0349

Cited by 8 publications

(3 citation statements)

References 50 publications

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“…Clinical variables affecting global HRQoL are not easy to modify, but consistent efforts to reduce recurrence have improved long-term outcomes. In particular, postoperative ileus has been addressed by systematic efforts for early mobilisation, and bowel obstruction has been improved over time through the increased use of laparoscopic surgery [ 33 – 35 ].…”

Section: Discussionmentioning

confidence: 99%

Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries

Andersson,

Angenete,

Gellerstedt

et al. 2024

Int J Colorectal Dis

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Purpose Rectal cancer and its treatment have a negative impact on health-related quality of life (HRQoL). If risk factors for sustained low HRQoL could be identified early, ideally before the start of treatment, individualised interventions could be identified and implemented to maintain or improve HRQoL. The study aimed to develop a multivariable prediction model for global HRQoL 12 months after rectal cancer treatment. Methods Within COLOR II, a randomised, multicentre, international trial of laparoscopic and open surgery for rectal cancer, a sub-study on HRQoL included 385 patients in 12 hospitals and five countries. The HRQoL study was optional for hospitals in the COLOR II trial. EORTC QLQ-C30 and EORTC QLQ-CR38 were analysed preoperatively and at 1 and 12 months postoperatively. In exploratory analyses, correlations between age, sex, fatigue, pain, ASA classification, complications, and symptoms after surgery to HRQoL were studied. Bivariate initial analyses were followed by multivariate regression models. Results Patient characteristics and clinical factors explained 4–10% of the variation in global HRQoL. The patient-reported outcomes from EORTC QLQ-C30 explained 55–65% of the variation in global HRQoL. The predominant predictors were fatigue and pain, which significantly impacted global HRQoL at all time points measured. Conclusion We found that fatigue and pain were two significant factors associated with posttreatment global HRQoL in patients treated for rectal cancer T1-T3 Nx. Interventions to reduce fatigue and pain could enhance global HRQoL after rectal cancer treatment. Trial registration This trial is registered with ClinicalTrials.gov No. NCT00297791

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Section: Discussionmentioning

confidence: 99%

Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries

Andersson,

Angenete,

Gellerstedt

et al. 2024

Int J Colorectal Dis

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“…Die vorliegende Evidenz unterstreicht die Notwendigkeit für Kliniker, ▪ geriatrische Assessments in die tägliche Praxis zu implementieren, ▪ die zentrale Rolle der Prähabilitation und ▪ die Bedeutung von ERAS-Konzepten [35]. Merke Zu den operativen Herausforderungen zählt die zeitnahe und belastungsstabile Versorgung von Frakturen.…”

Section: Onkologische Operationunclassified

Chirurgie im hohen Lebensalter

Knoblauch,

Saller,

Renz

2024

Intensivmedizin up2date

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“…Recent research has also highlighted the value of preoperative physical enhancement (i.e., "pre-habilitation") for improving frailty status [11,12]. The available evidence emphasizes the need for clinicians to implement geriatric assessments in daily practice, the pivotal role of prehabilitation, and the importance of enhanced recovery after surgery (ERAS) pathways [13].…”

Section: Introductionmentioning

confidence: 99%

Frailty and Colorectal Surgery: Review and Concept of Cancer Frailty

Maeda,

Takahashi,

Seo

et al. 2023

JCM

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Frailty is characterized by reduced physiological reserves across multiple systems. In patients with frailty, oncological surgery has been associated with a high rate of postoperative complications and worse overall survival. Further, given that cancer and frailty can co-exist in the same patient, cancer and cancer-related symptoms can rapidly accelerate the progression of baseline frailty, which we have termed “cancer frailty”. This distinction is clinically meaningful because the prioritization of interventions and the treatment outcomes may differ based on health conditions. Specifically, in patients with cancer frailty, improvements in frailty may be achieved via surgical removal of tumors, while prehabilitation may be less effective, which may in turn result in delayed treatment and cancer progression. In this review, we focused on challenges in the surgical treatment of non-metastatic colorectal cancers in patients with frailty, including those related to decision making, prehabilitation, and surgery. Potential recommendations for treating patients with cancer frailty are also discussed.

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Efficacy and Safety of Enhanced Recovery After Surgery Pathway in Minimally Invasive Colorectal Cancer Surgery: A Systemic Review and Meta-Analysis

Cited by 8 publications

References 50 publications

Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries

Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries

Chirurgie im hohen Lebensalter

Frailty and Colorectal Surgery: Review and Concept of Cancer Frailty

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