Efficacy and Safety of finerenone therapy in patients with cardiovascular and chronic kidney diseases in type 2 diabetes mellitus: a systematic review and meta-analysis
Abstract:Background and Aims: Finerenone, a nonsteroidal MR antagonist
(MRA), enhances renal and cardiovascular outcomes in patients with type
2 diabetes (T2DM). Finerenone’s safety and effectiveness in renal
function are debatable. This meta-analysis evaluates the efficacy and
safety of treatments for patients with diabetic kidney disease.
Methods: To find relevant RCTs, the databases PubMed, Embase,
and Google Scholar were searched. Finerenone’s effects were quantified
using estimated pooled mean differences (MDs… Show more
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