Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer

Abstract

This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population.A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study.Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study.This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.

Postoperative radiotherapy in pIIIA-N2 non–small cell lung cancer after complete resection and adjuvant chemotherapy: A meta-analysis

“…PORT with intensity-modulated radiotherapy or 3-dimensional conformal radiotherapy could guarantee sufficient irradiation doses to the target volume and decrease doses to organ at risk. [ 24 ] However, the improvement of local–regional free survival did not translate into improvement of DFS or OS. The possible interpretations were the following: As pIIIA-N2 NSCLC is a heterogeneous group of diseases, some patients could benefit from PORT, but not all patients.…”