Efficacy and safety of laparoscopic common bile duct exploration via choledochotomy with primary closure for the management of acute cholangitis caused by common bile duct stones

Abstract

Background T-tube drainage after laparoscopic common bile duct exploration (LCBDE) has been demonstrated to be safe and effective for patients with acute cholangitis caused by common bile duct stones (CBDSs). The outcomes after LCBDE with primary closure in patients with CBDS-related acute cholangitis are unknown. The present study aimed to evaluate the efficacy and safety of LCBDE with primary closure for the management of acute cholangitis caused by CBDSs. Methods Between June 2015 and June 2020, 368 consecutive patients with choledocholithiasis combined with cholecystolithiasis, who underwent laparoscopic cholecystectomy (LC) + LCBDE in our department, were retrospectively reviewed. A total of 193 patients with CBDS-related acute cholangitis underwent LC + LCBDE with primary closure of the CBD (PC group) and 62 patients underwent LC + LCBDE followed by T-tube placement (T-tube group). A total of 113 patients who did not have cholangitis were excluded. The clinical data were compared and analyzed. Results There was no mortality in either group. No significant differences were noted in morbidity, bile leakage rate, retained CBD stones, or readmission rate within 30 days between the two groups. Compared with the T-tube group, the PC group avoided T-tube-related complications and had a shorter operative time (121.12 min vs. 143.37 min) and length of postoperative hospital stay (6.59 days vs. 8.81 days). Moreover, the hospital expenses in the PC group were significantly lower than those in the T-tube group ($4844.47 vs. $5717.22). No biliary stricture occurred during a median follow-up of 18 months in any patient. No significant difference between the two groups was observed in the rate of stone recurrence. Conclusions LCBDE with primary closure is a safe and effective treatment for cholangitis caused by CBDSs. LCBDE with primary closure is not inferior to T-tube drainage for the management of CBDS-related acute cholangitis in suitable patients.

The efficacy and safety of laparoscopic common bile duct exploration with primary duct closure for cholecystolithiasis combined with choledocholithiasis

“…If bile leakage is still found, the suture can be added until there is no obvious leakage.Recurrence is a relatively rare complication. In this study, there were 2 (2.7%) cases and 4 (4.9%) cases of recurrence in the two groups, which is similar to the results of Wang et al 33 We believe that the recurrence is related to the patient's genetics, living environment, eating habits and previous operations. If recurrence of stones is found, ERCP lithotomy is recommended.…”

Laparoscopic transcystic common bile duct exploration following prior gastrectomy: the safety and feasibility Running head: Laparoscopic transcystic common bile duct exploration

“…LCBDE is a common surgical method for the treatment of gallstones and CBD stones, but about 15% of patients with T-tube drainage will have complications such as water and sodium electrolyte disorders, biliary peritonitis after T-tube removal, and T-tube displacement [17][18][19] . At present, the literature is more and more inclined to primary suture [20][21][22][23] .…”

Current management of concomitant cholelithiasis and common bile duct stones

“…Primary closure of the CBD without T-tube placement after LCBDE has been proposed as a safe and feasible choice even in patients ≥ 70-years-old[ 46 ] and in cases of acute cholangitis[ 47 ]. In patients > 75-years-old, one-stage LC and CBDE were found to be better than two-stage ERCP-ES and LC.…”