Abstract:IntroductionOur purpose of this study is to evaluate the effect and safety of macitentan in the treatment of pulmonary hypertension (PH).MethodsWe retrieved the safety and efficacy of macitentan treatment for PH using PubMed, the Cochrane Library, EMBASE databases and clinicaltrials.gov. The Cochrane Risk of Bias Tool was used for literature screening and quality assessment. Data analysis was conducted using RevMan 5.4.1 and Stata/SE 15.1 software. Results are presented as standardization mean differences (SMD… Show more
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