Efficacy and safety of percutaneous renal biopsy performed using 18G needle versus 16G needle: a single-center retrospective study

Xu, Sen-yin; Ma, Lili; Lin, Jiazhen; Zhang, Zhengxian; Wang, Xiaoya; Yin, Jiazhen

doi:10.1007/s11255-022-03276-4

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…Theoretically, the larger lumen of the 16-gauge needle should allow for more tissue to be harvested during each pass, thus increasing the potential for obtaining more glomeruli. However, contrary to our study findings, [ 24 ] found no significant difference in the number of glomeruli obtained between 16- and 18-gauge needles. This discrepancy might be attributed to sample size or technique variations across the studies.…”

Section: Discussioncontrasting

confidence: 99%

“…The use of 16-gauge needle was associated with an increased mean number of obtained glomeruli, which is consistent with previous literature included in the current review [ 8 , 13 , 16 , 18–20 , 22 , 24 ]. Theoretically, the larger lumen of the 16-gauge needle should allow for more tissue to be harvested during each pass, thus increasing the potential for obtaining more glomeruli.…”

Section: Discussionsupporting

confidence: 90%

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Comparison of outcomes of an 18-gauge vs 16-gauge ultrasound-guided percutaneous renal biopsy: a systematic review and meta-analysis

Zhan,

Lou

2023

Renal Failure

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Background: The needle size used in ultrasound-guided percutaneous renal biopsy significantly influences the efficacy and safety of the procedure. The aim of this study is to perform a comparative analysis of 16-gauge and 18-gauge needles for ultrasound-guided percutaneous renal biopsy. Methods: This systematic review and meta-analysis included randomized controlled trials and observational studies that compared the outcomes of using 18-gauge and 16-gauge needles for ultrasound-guided percutaneous renal biopsy. The efficacy parameters included a mean number of glomeruli obtained and the number of passes, while the safety parameters focused on the rate of complications. We searched multiple databases, assessed the risk of bias, and conducted statistical analyses using appropriate models. Results: Fifteen studies were included. Compared to the 18-gauge needle, the use of 16-gauge needle for the biopsy was associated with the significantly higher mean number of glomeruli obtained (pooled SMD 0.61, 95%CI: 0.32 to 0.89; p < 0.001) and fewer required passes (pooled SMD −0.57, 95%CI: −0.97 to −0.18; p = 0.004). No significant difference was observed in the individual safety parameters, including pain, hematuria, need for blood transfusion, major, and minor complications. However, the use of 16-gauge needle was associated with higher odds of total complications (pooled OR 1.57, 95%CI: 1.16 to 2.13; p = 0.004). Conclusion: While the 16-gauge needle for ultrasound-guided percutaneous renal biopsy offers improved efficacy in terms of a higher mean number of glomeruli and fewer required passes, it is associated with higher total complications. A judicious needle size selection that would consider patient-specific factors and risk-benefit ratio, is crucial for optimizing patient outcomes.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 90%

Comparison of outcomes of an 18-gauge vs 16-gauge ultrasound-guided percutaneous renal biopsy: a systematic review and meta-analysis

Zhan,

Lou

2023

Renal Failure

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“…Unfortunately, invasive renal biopsy has a considerable risk of serious complications (e.g., gross hematuria, perirenal hematoma, arteriovenous fistula, etc.) ( 9 ). Hence, a non-invasive method of monitoring renal function and assessing RF would be a valuable tool to diagnose CKD and guide antifibrotic therapy.…”

Section: Introductionmentioning

confidence: 99%

Native T1 mapping for non-invasive quantitative evaluation of renal function and renal fibrosis in patients with chronic kidney disease

Wei¹,

Zhang²,

Zhang³

et al. 2023

Quant Imaging Med Surg

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Background To investigate the role of native T 1 mapping in the non-invasive quantitative assessment of renal function and renal fibrosis (RF) in chronic kidney disease (CKD) patients. Methods A prospective analysis of 71 consecutive patients [no RF (0%): 9 cases; mild RF (<25%): 36 cases; moderate RF (25–50%): 17 cases; severe RF (>50%): 9 cases] who were clinically diagnosed with CKD that was pathologically confirmed and who underwent magnetic resonance imaging (MRI) examination between October 2021 and September 2022 was performed. T 1 -C (mean cortical T 1 value), T 1 -M (mean medullary T 1 value), ΔT 1 (mean corticomedullary difference) and T 1 % (mean corticomedullary ratio) values were compared. Correlations between T 1 parameters and clinical and histopathological values were analyzed. Regression analysis was performed to determine independent predictors of RF. The areas under the receiver operating characteristic curve (AUC) were calculated to assess the diagnostic value of RF. Results The T 1 -C, ΔT 1 and T 1 % values (P<0.05) were significantly different in the CKD group, but T 1 -M was not (P>0.05). The ΔT 1 and T 1 % values showed significant differences in pairwise comparisons among CKD subgroups (P<0.05) except for CKD 2 and 3. ΔT 1 and T 1 % were moderately correlated with the estimated glomerular filtration rate (ΔT 1 : r s =−0.561; T 1 %: r=−0.602), serum creatinine (ΔT 1 : r s =0.591; T 1 %: r s =0.563), blood urea nitrogen (ΔT 1 : r s =0.433; T 1 %: r s =0.435) and histopathological score (ΔT 1 : r s =0.630; T 1 %: r s =0.658). ΔT 1 and T 1 %, but not T 1 -C, were independent predictors of RF (P<0.05). ΔT 1 and T 1 % were set as −410.07 ms and 0.8222 with great specificity [ΔT 1 : 91.7% (77.5–98.2%); T 1 %: 97.2% (85.5–99.9%)] to identify mild RF and moderate-severe RF. The optimal cutoff values for differentiating severe RF from mild-moderate RF were −343.81 ms (ΔT 1 ) and 0.8359 (T ...

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Comparative Study Between Variable Flip Angle and Modified Look–Locker Inversion Recovery for Evaluating Renal Interstitial Fibrosis

Hua,

Zhuang,

Wang

et al. 2024

Magnetic Resonance Imaging

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BackgroundVariable flip angle (VFA) and modified Look–Locker inversion recovery (MOLLI) are frequently used for noninvasive evaluation of renal interstitial fibrosis (IF) in chronic kidney disease (CKD). However, controversy remains over which method is preferred.PurposeTo compare the diagnostic efficacy of VFA and MOLLI for T1 mapping in evaluating renal IF.Study TypeProspective.SubjectsFifty‐one participants with CKD (CKD stage 1–5, 35 males) and 18 healthy volunteers (eight males).Field Strength/Sequence3.0 T, three‐dimensional gradient echo sequence for B1+ VFA, and two‐dimensional gradient echo sequence for MOLLI.AssessmentImage quality was assessed on a five‐point scale. Cortex and medulla T1 values (cT1 and mT1), corticomedullary T1 value difference (ΔT1, medulla − cortex), and corticomedullary T1 value ratio (ratio T1, cortex:medulla) were compared between VFA and MOLLI as well as between IF grade (0–4) based on biopsy.Statistical TestsIntraclass correlation coefficient, Bland–Altman analysis, analysis of variance, Kruskal–Wallis test, correlation analysis, and receiver operating characteristics analysis with the area under the curve (AUC). P‐value <0.05 was considered significant.ResultsMOLLI provided significantly better image quality compared to VFA. cT1 and mT1 values significantly differed between VFA and MOLLI (cT1‐VFA: 1771.4 ± 139.4 msec vs. cT1‐MOLLI: 1729.9 ± 132.1 msec; mT1‐VFA: 2076.0 [interquartile range (IQR): 2045.9–2129.9] msec vs. mT1‐MOLLI: 2039.2 [IQR: 1997.8–2071.6] msec). ΔT1 and ratio T1 values were not different between VFA and MOLLI (ΔT1: 300.8 ± 71.4 vs. 306.0 ± 78.4, respectively, P = 0.33 and ratio T1: 0.85 ± 0.038 vs. 0.85 ± 0.041, respectively, P = 0.064). No difference was observed between T1 variables and T1 mapping methods in diagnosing IF.Data ConclusionΔT1 and ratio T1 were not different between VFA and MOLLI. Both VFA and MOLLI are effective for noninvasive assessment of renal IF.Level of Evidence2Technical EfficacyStage 2

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Efficacy and safety of percutaneous renal biopsy performed using 18G needle versus 16G needle: a single-center retrospective study

Cited by 4 publications

References 20 publications

Comparison of outcomes of an 18-gauge vs 16-gauge ultrasound-guided percutaneous renal biopsy: a systematic review and meta-analysis

Comparison of outcomes of an 18-gauge vs 16-gauge ultrasound-guided percutaneous renal biopsy: a systematic review and meta-analysis

Native T1 mapping for non-invasive quantitative evaluation of renal function and renal fibrosis in patients with chronic kidney disease

Comparative Study Between Variable Flip Angle and Modified Look–Locker Inversion Recovery for Evaluating Renal Interstitial Fibrosis

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