Efficacy and Safety of Percutaneous Microwave Ablation and Cementoplasty in the Treatment of Painful Spinal Metastases and Myeloma

Abstract

Microwave ablation is an effective and safe treatment technique for painful spinal metastases. Further studies may be helpful in determining the role of microwave ablation in locoregional control of metastases.

Combination of Microwave Ablation and Percutaneous Osteoplasty for Treatment of Painful Extraspinal Bone Metastasis

“…Therefore, the main goal of treatment is to reduce pain and prevent pathologic fractures. Imaging-guided ablation techniques have potential advantages in the treatment of bone metastases, including low operating costs, real-time imaging guidance, synergy with other treatments, reproducibility, and short operating time (6-10, [14][15][16]. Given the significant effect in reducing pain, ablation therapy has been included in clinical guidelines for bone metastases (24).…”

“…Osteoplasty can enhance bone stability and has a good effect on preventing and treating osteoporosis and pathologic fractures (11)(12)(13). However, there are few reports about the combination of MW ablation and osteoplasty, and there are even fewer reports about the combination of both therapies in extraspinal bone metastases (14)(15)(16). Since anatomic locations often confer different challenges to the treating physician, spinal and extraspinal bone metastases are examined separately.…”

Percutaneous Interventional Techniques for Treatment of Spinal Metastases

“…Recent advances and evolution of percutaneous minimally invasive thermal ablation technologies with or without vertebral augmentation offer attractive options for certain subgroups of patients with spinal metastases (such as suboptimal response or contraindications to radiation therapy) with several distinct advantages including timely and durable pain palliation, excellent local tumor control rates, reinforcement of the treated vertebra, as well as short-and longterm improvement in functional status without compromise in adjuvant radiation or chemotherapy. [6][7][8][9][10][11][12][13][14]…”

“…Percutaneous thermal ablation has been established as part of the treatment paradigm for the management of vertebral metastases. [6][7][8][9][10][11][12][13][14][15][16] The goals of treatment are typically pain palliation and/or local tumor control (often with vertebral augmentation for pathologic fracture stabilization or prevention) for majority of the patients. In addition, osseous oligometastases (less than five lesions) may be approached for definitive cure.…”

“…5 Over the past two decades, there have been substantial advances in minimally invasive percutaneous management of vertebral metastases including thermal ablation with or without vertebral augmentation that may be performed in conjunction with (or supplemented by) adjuvant radiation therapy, chemotherapy, or surgery. [6][7][8][9][10][11][12][13][14] This review details an approach for evaluation as well as minimally invasive percutaneous treatment of spinal metastases focusing on thermal ablation and most recent advances.…”