Efficacy and Safety of Sclerotherapy Using Polidocanol Foam: A Controlled Clinical Trial

Alós, Jesús Garanto; Carreño, Patricia Tejera; López, José Antonio García; Estadella, B.; Serra‐Prat, Mateu; Marinello, J

doi:10.1016/j.ejvs.2005.08.018

Cited by 118 publications

(106 citation statements)

References 12 publications

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“…42 43 reported a statistically significant difference at the 5% level between treatment arms for nerve injury, which favoured EVLA over surgery. Only Alos et al 119 reported a statistically significant difference at the 1% level between treatment arms for pigmentation, which favoured LS over FS. Only Carradice et al 86 reported a statistically significant difference between treatment arms for any other adverse event, with fewer incidents of sensory disturbance in the EVLA arm than the surgery arm (2 vs. 13; p = 0.02).…”

Section: Assessment Of Clinical Effectivenessmentioning

confidence: 99%

“…Twelve trials 42,44,55,81,88,89,90,95,97,98,119,112 reported data on the failure of the initial procedure (i.e. the intervention failed to strip the vein successfully or the vein was not occluded or obliterated, or open segments remained) within the first few days post operation up to 1 month (see Table 11).…”

Section: Failure Of Proceduresmentioning

confidence: 99%

“…Only three trials [119][120][121] included LS as a comparator (with FS) (see Table 8). The principal common comparator was therefore surgery (i.e.…”

Section: Includedmentioning

confidence: 99%

“…amount or duration of analgesic use), but the heterogeneous nature of the data measurement rendered them unsuitable for inclusion in any analysis. 39,55,[78][79][80][84][85][86][87]89,91,97,98,119,124,128 Details of the outcomes data are given in Tables 11-16. The results of the meta-analyses, where meta-analysis was possible for these outcomes, are reported in Quantitative analysis.…”

Section: Pain Scorementioning

confidence: 99%

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Clinical effectiveness and cost-effectiveness of minimally invasive techniques to manage varicose veins: a systematic review and economic evaluation

Carroll

Hummel²,

Leaviss³

et al. 2013

Health Technology Assessment

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Section: Assessment Of Clinical Effectivenessmentioning

confidence: 99%

Section: Failure Of Proceduresmentioning

confidence: 99%

“…Only three trials [119][120][121] included LS as a comparator (with FS) (see Table 8). The principal common comparator was therefore surgery (i.e.…”

Section: Includedmentioning

confidence: 99%

Section: Pain Scorementioning

confidence: 99%

See 2 more Smart Citations

Clinical effectiveness and cost-effectiveness of minimally invasive techniques to manage varicose veins: a systematic review and economic evaluation

Carroll

Hummel²,

Leaviss³

et al. 2013

Health Technology Assessment

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“…Similar follow-up has also been suggested by several other authors. [12][13][14][15] An ultrasound examination was done a week after therapy showed optimum obliteration of the treated vein in all the cases and also showed no signs of DVT. Thus re-sclerotherapy was not required.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of ultrasound guided foam sclerotherapy with sodium tetradecyl sulphate for residual and minor varicosities

et al. 2017

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Background: Ultrasound-guided foam sclerotherapy (UGFS) is becoming an accepted standard of treatment varicose veins. It is a relatively safe, effective inexpensive method in limited, small varicose veins.This study aims to assess the safety and efficacy of UGFS using sodium tetradecyl sulphate (setrol) in patients presenting with minor varicosities and residual varicosities of lower limb.Methods: 78 patients with minor varicosities or residual varicosities post-surgery who presented between January2015 and June2016 at KR hospital attached to Mysore Medical College and Research Institute, Mysuru, underwent ultrasound-guided foam sclerotherapy with 0.5ml (at a single session) setrol prepared as a foam by Tessari technique. The efficacy criterion was the disappearance of the varicosities and improvement in symptoms and signs: 1 week, and 1, 3, 6 and 12 months after the treatment. Complications of sclerotherapy were reported during follow-up.Results: Decrease or withdrawal of complaints was reported in 96% of cases (74 patients). Disappearance or decrease of varicose veins was observed in all patients (100%). Phlebitis and pigmentation as a complication was noted in 5 (7%) and 9 (11.5%) cases respectively. Major complications, such as deep vein thrombosis, pulmonary embolism, dyspnoea, anaphylaxis, or neurological abnormalities, were not reported.Conclusions: Ultrasound-guided foam sclerotherapy for minor varicosities and residual varicosities with sodium tetra decyl sulphate is a safe and satisfactory method of treatment of minor and residual varicosities.

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Injection sclerotherapy for varicose veins

Oliveira

Riera

Vasconcelos

et al. 2021

Cochrane Database of Systematic Reviews

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Efficacy and Safety of Sclerotherapy Using Polidocanol Foam: A Controlled Clinical Trial

Abstract: Efficacy of venous sclerosis with foam seems to be greater than with liquid although there is a higher risk of minor secondary effects.

Cited by 118 publications

References 12 publications

Clinical effectiveness and cost-effectiveness of minimally invasive techniques to manage varicose veins: a systematic review and economic evaluation

Clinical effectiveness and cost-effectiveness of minimally invasive techniques to manage varicose veins: a systematic review and economic evaluation

Efficacy and safety of ultrasound guided foam sclerotherapy with sodium tetradecyl sulphate for residual and minor varicosities

Injection sclerotherapy for varicose veins

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