Efficacy and safety of thread embedding acupuncture for facial expression muscles atrophy after peripheral facial paralysis: study protocol for a randomized controlled trial

Yu, Bo; Xuan, Ling; Jin, Yutong; Chen, Shan; Liu, Shan; Wan, Yi-Jia

doi:10.1186/s13063-021-05696-6

Cited by 6 publications

(2 citation statements)

References 39 publications

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“…Minimally invasive buried thread implantation level of accuracy and enhanced clinical e cacy [41][42] [43]. Acupuncture point buried thread procedures are easy to use, safe, and can shorten patient visits while increasing patient compliance.…”

Section: Discussionmentioning

confidence: 99%

The "tonifying the kidneys, resolving blood stasis and clearing collaterals" method in polycystic ovary syndrome (PCOS) research: study protocol for a multicentre cohort study nested randomised controlled trials

Song,

liu,

Yang

et al. 2024

Preprint

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Introduction: Polycystic ovary syndrome (PCOS) presents as a multi-complicated syndrome and increases the risk of other diseases. Life management is clinically ineffective as a first-line basic treatment for polycystic ovary syndrome. Acupuncture and Chinese herbal medicine (CHM) have excellent clinical efficacy for PCOS. however,there is currently a dearth of high-quality data demonstrating its efficacy.The purpose of this experiment is to assess the safety and efficacy, especially the long-term efficacy,of individualized life management、CHM, acupoint thread-embedding therapy for treating PCOS. Methods and analysis: We present a multicentre, prospective, combined randomised clinical trial and observational cohort study design, with a target sample size of 316 patients with PCOS of the kidney deficiency and blood stasis type aged between 18-45years. Patients were divided into an observational cohort with a renal supplementation and blood-stasis-restoration cohort based on whether or not they were exposed to the tonifying-kidney, resolving-blood stasis-and-tongue method. Based on the examination results, the observation cohort received individualised life management and appropriate pharmacological interventions and was followed up for 6 months. The kidney tonifying and resolving stasis through the channels cohort was randomly divided into A) Kidney tonifying and resolving stasis traditional Chinese medicine group, B) Kidney tonifying and resolving stasis buried under ultrasound in the musculoskeletal bone group, and C) Kidney tonifying and resolving stasis traditional Chinese medicine combined with burying group by the method of randomised numerical table based on the above. The kidney tonifying and resolving stasis through the channels cohort treatment cycle was 3 months, and the follow-up period was 3 months. Main results: (1) the change of menstrual of PCOS patients before and after treatment ; (2) the efficacy of traditional Chinese medicine symptoms. Secondary results: Sex hormones, AMH, ultrasound;changes in scores such as polycystic cognition,PCOSQ-50 score,menstruation,hirsutism,Ffq168,IPAQ-SFHADS etc.All assessments were followed up with redcap questionnaires at baseline at weeks 4, 8, and 12 after the start of the intervention and at weeks 16, 20, and 24 after the end of the intervention. Trial registration number: (2023) Lun Shen No.41; Pre-results.The trial was launched on July 2023 through https://www.chictr.org.cn/ Registrationnumber:ChiCTR2300073832.

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Section: Discussionmentioning

confidence: 99%

The "tonifying the kidneys, resolving blood stasis and clearing collaterals" method in polycystic ovary syndrome (PCOS) research: study protocol for a multicentre cohort study nested randomised controlled trials

Song,

liu,

Yang

et al. 2024

Preprint

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“…The acupoints on the limbs and trunk were applied bilaterally. The selection of acupoints is based on previous research and our clinical experience[ 22 , 23 ] (Fig. 1 ).…”

Section: Methodsmentioning

confidence: 99%

Laser acupuncture and photobiomodulation therapy in Bell’s palsy with a duration of greater than 8 weeks: a randomized controlled trial

Wu,

Lan,

Litscher

et al. 2024

Lasers Med Sci

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To investigate the efficacy of laser acupuncture and photobiomodulation therapy in alleviating symptoms among patients diagnosed with Bell’s palsy with duration of greater than 8 weeks. The randomized controlled trial has been performed from May 2021 to April 2023. Patients were eligible who had Bell’s palsy with duration of greater than 8 weeks on out-patient Department of Otorhinolaryngology in Beijing Tongren Hospital. The laser acupuncture group received class IV laser treatment for 3 times per weeks, a total of 72 times. The control group received the same treatment procedure except the laser parameter. The primary outcome measures comprised House–Brackmann facial nerve grading system and electroneurography. Secondary outcome measures comprised Sunnybrook facial grading system, electromyography, and the blink reflex. A total of 84 participants were included (42 control group, 42 laser acupuncture group). After treatment, House–Brackmann facial nerve grading system (OR, 0.11; 95% CI, 0.04–0.30; P < 0.001), and the pathologic numbers of electroneuronography were statistically different between the laser acupuncture group and control group, including orbicularis oculi (OR,0.08; 95% CI, 0.02–0.21; P < 0.001), Frontalis muscle (OR,0.14; 95% CI, 0.05–0.39; P < 0.001), Orbicularis oris (OR,0.13; 95% CI, 0.04–0.36; P < 0.001), Ala nasi muscle (OR,0.06; 95% CI, 0.02–0.18; P < 0.001). In secondary outcomes, Sunnybrook facial grading system, has significant difference between the two groups (20.26; 95% CI, 14.69 to 25.83; P < 0.01). Latency by ENoG, include orbicularis oculi (-0.61; 95% CI, -0.43 to -0.09; P < 0.001), frontalis muscle (-0.12; 95% CI, -0.21 to -0.03; P < 0.01), orbicularis oris (-0.28; 95% CI, -0.41 to -0.16; P < 0.001), and ala nasi muscle (-0.26; 95% CI, -0.38 to -0.16; P < 0.001). All amplitudes of MUAPs and durations by electromyography (EMG) showed statistically significant differences compared with the control group after treatment. For the frontalis muscle, the amplitude of MUAPs was -64.23 (95% CI, -80.89 to -47.56; P < 0.001) and duration was -1.18 (95% CI, -1.49 to -0.87; P < 0.001). For orbicularis oris, amplitude of MUAPs was -29.82 (95% CI, -55.03 to -4.62; P = 0.02) and duration was -0.57 (95% CI, -0.94 to -0.20; P < 0.001). For depressor angulli oris, amplitude of MUAPs was -47.06 (95% CI, -62.15 to -31.97; P < 0.001) and duration was -2.21 (95% CI, -2.69 to -1.72; P < 0.001). Blink reflex, including R1 (OR, 0.03; 95% CI, 0.01–0.16; P < .001), R2 (OR, 0.04; 95% CI, 0.004–0.29; P < .001), and R2 latency differences (OR, 0.15; 95% CI, 0.05–0.51; P < .001), have significant difference between the two groups, respectively. The findings suggest that laser acupuncture relieve symptoms for patients with Bell’s palsy with a duration of greater than 8 weeks.Trial registration: ClinicalTrials.gov Identifier: NCT05846217.

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Super-Selective Intra-arterial Thrombolytic Therapy for Peripheral Facial Paralysis After Postauricular Hyaluronic Acid Injection for the Esthetic Correction of Lying Ears

Zheng,

Pei,

Zhou

et al. 2024

Aesth Plast Surg

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Efficacy and safety of thread embedding acupuncture for facial expression muscles atrophy after peripheral facial paralysis: study protocol for a randomized controlled trial

Cited by 6 publications

References 39 publications

The "tonifying the kidneys, resolving blood stasis and clearing collaterals" method in polycystic ovary syndrome (PCOS) research: study protocol for a multicentre cohort study nested randomised controlled trials

The "tonifying the kidneys, resolving blood stasis and clearing collaterals" method in polycystic ovary syndrome (PCOS) research: study protocol for a multicentre cohort study nested randomised controlled trials

Laser acupuncture and photobiomodulation therapy in Bell’s palsy with a duration of greater than 8 weeks: a randomized controlled trial

Super-Selective Intra-arterial Thrombolytic Therapy for Peripheral Facial Paralysis After Postauricular Hyaluronic Acid Injection for the Esthetic Correction of Lying Ears

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