Efficacy and tolerability of vaginal progesterone capsules (Utrogest™ 200) compared with progesterone gel (Crinone™ 8%) for luteal phase support during assisted reproduction

Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support

“…The results show a similar efficiency of both preparations, producing almost identical pregnancy rates. Our results are in agreement with other studies (32,33) reporting comparable IVF success with the use of both supplements.…”

Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study

“…Our results are supported by other researchers who observed similar efficacy with dydrogesterone and natural micronized P in women undergoing IVF-ET (29,31,32). Further, a prospective randomized study comparing vaginal gel and vaginal capsules for LPS showed the ongoing pregnancy rate to be comparable between the two groups (33,34). Another group observed identical pregnancy rates between the gel and micronized P intravaginal capsules.…”

Single and multidose pharmacokinetic study of a vaginal micronized progesterone insert (Endometrin) compared with vaginal gel in healthy reproductive-aged female subjects

“…Progesterone is available for vaginal administration (17)(18)(19)(20)(21)(22)(23)(24). Its pharmacokinetics compare favorably with oral administration.…”