Efficacy and Tolerance of Metamizole versus Morphine for Acute Pancreatitis Pain

Peiró, Ana M.; Martínez, Juan; Martínez, Eduardo Alberto Rodriguez; de-Madaria, Enriqué; Llorens, Pere; Horga, J.F.; Pérez‐Mateo, Miguel

doi:10.1159/000114852

Cited by 80 publications

(70 citation statements)

References 25 publications

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“…However, parenteral fluid and electrolyte supplementation and treatment to relieve pain and prevent infection are provided during this time (11,12). In addition, AP often produces intense and persistent pain, so pain control is required (16,17). One recent retrospective study suggested that feeding can be started orally, upon admission, without increasing the pain severity and length of the hospital stay (18) Those researchers also suggested that the fat content in the food did not seem to be associated with increased pain levels or the length of the hospital stay (18).…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Appak¹,

Karakoyun²,

Cetin³

et al. 2018

Iran J Pediatr

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Background: Pancreatitis can be seen at any age in childhood. Therefore, it is important for pediatricians to know the diagnosis and the management of pancreatitis. Objectives: The aim of this study was to evaluate the etiological factors, clinical features and management of pancreatitis in children. Methods: This study included hospitalized children who were diagnosed with pancreatitis. The clinical presentations, laboratory analyses, radiological features, etiologies and treatments were recorded. Results: A total of 59 pancreatic attacks were recorded in 41 patients. The most common symptoms were abdominal pain and vomiting, and the most common etiological cause was idiopathic. Approximately 22% of the patients had acute recurrent episodes. Somatostatin was used to treat 61% of the attacks; however, it did not reduce the time to recovery after an attack when compared to those patients who did not use somatostatin (P = 0.36). The white blood cell counts and urea and calcium levels were significantly different between those patients who did and did not use somatostatin. Seventeen (28.8%) of the pancreatitis attacks were determined to be severe. Moreover, a mutation in the cystic fibrosis transmembrane conductance regulator was detected in two patients with recurrent pancreatitis. Conclusions: Fever and irritability can be signs of pancreatitis in infants and toddlers. In our cases, the somatostatin treatment was not effective in terms of the time to recovery after an attack.

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Section: Discussionmentioning

confidence: 99%

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Appak¹,

Karakoyun²,

Cetin³

et al. 2018

Iran J Pediatr

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“…Opioid derivatives are often used in the treatment of pain in acute pancreatitis; however, in manometric studies only high doses of morphine have been able to significantly increase basal pressure in the SO [23] . Trimebutine is also an opioid derivative with exclusive action on receptors of the Meissner and Auerbach plexus throughout the digestive tube.…”

Section: Discussionmentioning

confidence: 99%

Effect of Four Medications Associated with Gastrointestinal Motility on Oddi Sphincter in the Rabbit

Qian

Hou

2009

Pancreatology

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“…Aurrez uste zenaren aurka, morfina erabiltzeko inolako eragozpenik ez dago paziente hauetan (12).  Organo-gutxiegitasunaren balorazio egokia egin (13).…”

Section: Pankreatitis Akutua Duen Paziente Baten Arreta Larrialdi Zerunclassified

Pankreatitis akutua duen pazientearen artatzea

Zubia

2017

Osag

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LaburpenaPankreatitis akutua pankrearen gaixotasun onbera eta akutua da. Kasurik gehienetan arina izan ohi da, baina formarik larrienetan hilkortasun-eta konplikazio-tasa handiak izan ditzake. Kasu larri horietarako, oso garrantzitsua da espezialitate anitzeko protokolo bat izatea, maila ezberdinetan eman beharreko arreta hitzartua duena. Berrikuspen-lan honetan maila ezberdin bakoitzean eman beharreko arreta egokia deskribatzen da. Larrialdi Zerbitzuetan: Diagnostikoa egin, Analgesia egokia, Larritasun-mailaren balorazioa, Hidratazio egokia hasi. Ospitaleratze Unitateetan: Ezinbestekoa da pazientearen larritasuna modu kliniko eta analitikoan egiaztatzea, 12 orduan behin, lehen 48 orduetan. Edozein momentutan organo-gutxiegitasun datuak atzematen badira, pazientea Zainketa Intentsiboen Unitatean artatu behar da. Horretaz gain, honako neurri hauek hartuko dira: analgesia mantendu, hidratazio egokia eman, elikadura hasi, sabelalde barneko presioa neurtu, erradiologiaprobak egin. Antibiotiko enpirikoaren erabilera ez da gomendatzen. Kirurgiarako indikazioak: Tratamendu medikoarekin konpontzen ez den sabelalde barneko presioaren igoera larria, nekrosi infektatua (neurri minimoki inbaditzaileez saia liteke lehen urrats moduan, edo step-up estrategia), hesteen zulaketa, hemorragia akutua (erradiologia interbentzionista erabiltzen da normalean). Ondorioak: Pankreatitis akutua gaixotasun arina da gehienetan, baina kasurik larrienetan hilkortasuneta konplikazio-tasa altua ditu. Horiek artatzeko protokolo bat izatea eta parte hartzen duten espezialista ezberdinen elkarlana ezinbestekoa da.Gako-hitzak: pankreatitis akutua, protokolo klinikoa, kirurgia. Abstract Acute pancreatitis is an acute but benign disease of the pancreas. It is usually a mild illness, but in its

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Efficacy and Tolerance of Metamizole versus Morphine for Acute Pancreatitis Pain

Cited by 80 publications

References 25 publications

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Effect of Four Medications Associated with Gastrointestinal Motility on Oddi Sphincter in the Rabbit

Pankreatitis akutua duen pazientearen artatzea

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