Efficacy of 1.23% acidulated phosphate fluoride gel on non-cavitated enamel lesions: a randomized clinical trial

Goldenfum, Gabriela Maltz; Silva, Natália Caldeira; Almeida, Ingrid dos Anjos; Neves, Matheus; Silva, Berenice Barbachan e; Jardim, Juliana Jobim; Rodrigues, Jonas Almeida

doi:10.1590/1807-3107bor-2021.vol35.0038

Cited by 6 publications

(6 citation statements)

References 19 publications

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“…Acidulated fluorophosphate gel is the most commonly used professional topically applied fluoride gel [ 46 , 59 ]. However, topical application of acidulated fluorophosphate gel has no additional arresting effect on caries lesions [ 24 ]. Stannous fluoride has more antimicrobial properties than other fluoride compounds do [ 65 , 66 ].…”

Section: Fluoride-based Materialsmentioning

confidence: 99%

Bioactive Materials for Caries Management: A Literature Review

et al. 2023

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Researchers have developed novel bioactive materials for caries management. Many clinicians also favour these materials, which fit their contemporary practice philosophy of using the medical model of caries management and minimally invasive dentistry. Although there is no consensus on the definition of bioactive materials, bioactive materials in cariology are generally considered to be those that can form hydroxyapatite crystals on the tooth surface. Common bioactive materials include fluoride-based materials, calcium- and phosphate-based materials, graphene-based materials, metal and metal-oxide nanomaterials and peptide-based materials. Silver diamine fluoride (SDF) is a fluoride-based material containing silver; silver is antibacterial and fluoride promotes remineralisation. Casein phosphopeptide-amorphous calcium phosphate is a calcium- and phosphate-based material that can be added to toothpaste and chewing gum for caries prevention. Researchers use graphene-based materials and metal or metal-oxide nanomaterials as anticaries agents. Graphene-based materials, such as graphene oxide-silver, have antibacterial and mineralising properties. Metal and metal-oxide nanomaterials, such as silver and copper oxide, are antimicrobial. Incorporating mineralising materials could introduce remineralising properties to metallic nanoparticles. Researchers have also developed antimicrobial peptides with mineralising properties for caries prevention. The purpose of this literature review is to provide an overview of current bioactive materials for caries management.

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Section: Fluoride-based Materialsmentioning

confidence: 99%

Bioactive Materials for Caries Management: A Literature Review

et al. 2023

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“…Prevalensi karies pada tahun 2018 mengalami peningkatan dua kali lipat lebih dari tahun dari tahun 2013 yaitu 25,9% menjadi 57,6%. 3 Beberapa faktor terlibat dalam pencegahan karies gigi pada anak. Salah satu faktor yang paling efektif adalah penggunaan fluorida yang tepat.…”

Section: Latar Belakangunclassified

“…APF adalah agen kariostatik yang pertama kali diperkenalkan oleh Brudevold, et al pada tahun 1963. 3 Acidulated Phosphate Fluoride merupakan salah satu bahan fluorida yang dapat diaplikasikan secara topikal dan paling efektif dalam meningkatkan pelepasan fluor oleh material restorasi jika dibandingkan dengan bahan topikal aplikasi fluor lainnya.6 Aplikasi gel APF akan membentuk fluorapatit yang lebih tahan asam dan membantu proses remineralisasi pada email gigi. Email gigi sulung memiliki derajat porositas yang lebih tinggi, mengandung mineral kalsium dan fosfat yang lebih sedikit.…”

Section: Latar Belakangunclassified

“…Pentingnya, frekuensi menyikat gigi dan pengurangan plak dalam mengendalikan aktivitas karies. 41 Penelitian Maria Laura Menezes Bonow, et al pada tahun 2012 dengan 60 sampel (anak-anak usia 7-12 tahun) yang bertujuan untuk mengevaluasi efektivitas aplikasi gel 1,23% APF pada penangkapan lesi karies aktif yang baru terbentuk pada anak-anak. Hasil dari penelitian ini, tidak menunjukkan efek tambahan dari APF gel pada sampel anak-anak yang terpapar air fluorida dan pasta gigi ini dalam pencegahan lesi email dibandingkan dengan gel plasebo setelah 8 minggu.…”

Section: Pembahasanunclassified

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Acidulated phosphate fluoride sebagai bahan pencegahan Karies gigi anak : a scoping review (Laporan Penelitian)

Hayaza

Jeddy

Laksmiastuti

2022

JKGT

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Background: Caries occur in the hard tissues of the teeth due to bacterial activity in plaque. Untreated dental caries can result in pain, therefore early and if caries is left over time it will cause pain so that early caries prevention is necessary. Caries prevention can be done using Acidulated Phosphate Fluoride as an effective option in preventing the process of caries development in children. Aim: To know the effectiveness of APF gel 1,23% in preventing caries in children. Method: Scoping Review with inclusion criteria using a Randomized Controlled Trial (RCT) study design was conducted according to Preferres Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and two databases (PubMed and Google Scholar). Result: The results showed that the initial search yielded 985 documents. After eliminating duplicate studies and screening full-text articles for eligibility (n = 21), the authors identified 3 studies that met the criteria for inclusion. Conclusion: APF gel 1.23% has the effectiveness and preventing dental caries in children due to its better ability to bind calcium enamel,also does not irritate the gingiva..

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“…Infrequent toothbrushing is associated with greater caries incidence and increment in primary and permanent teeth [1]. Frequent toothbrushing reduces plaque accumulation and caries activity [2]. Less than twice daily toothbrushing at two and three years of age is associated with more caries at the age of 5 [3].…”

Section: Introductionmentioning

confidence: 99%

Unemployment and expenditure on health and education as mediators of the association between toothbrushing and global income inequalities

2022

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Objective The study assessed the association of country-level income inequalities with the percentage of schoolchildren toothbrushing-at-least-twice-daily; and the mediating effect of country-level unemployment rate and governmental expenditure on health and education (EH&E). Methods This was an ecological study. The dependent variable was country-level toothbrushing-at-least-twice-daily among 11-15-year-old schoolchildren. Data for the period 2009 to 2019 were extracted from two global surveys about schoolchildren’s health and from manuscripts identified through a systematic search of three databases. The independent variable was country-level income inequalities measured by the Gini coefficient (GC) extracted from the Sustainable Development Report 2021. The mediators were the unemployment rate and EH&E. We stratified the sample by the level of GC and assessed the correlation between the dependent and independent variables in each stratum. Linear regression was used to assess the relations between the dependent and independent variables, and mediation path analysis was used to quantify the direct, indirect, and total effects. Results Data were available for 127 countries. The mean (SD) percentage of children who brushed-at-least-twice-daily was 67.3 (16.1), the mean (SD) GC = 41.4 (8.2), unemployment rate = 7.5 (4.7) and EH&E = 8.4 (3.3). The percentage of children brushing at-least-twice-daily had weak and non-significant correlation with GC that was positive in countries with the least inequality and negative for countries with higher levels of inequality. A greater percentage of schoolchildren brushing-at-least-twice-daily was significantly associated with higher GC (B = 0.76, 95%CI: 0.33, 1.18), greater EH&E (B = 1.67, 95%CI: 0.69, 2.64) and lower unemployment rate (B=-1.03, 95%CI: -1.71, -0.35). GC had a significant direct positive effect (B = 0.76, 95%CI: 0.33, 1.18), a significant indirect negative effect through unemployment and EH&E (B=-0.47, 95%CI: -0.79, -0.24) and a non-significant total positive effect (B = 0.29, 95%CI: -0.09, 0.67) on the percentage of schoolchildren brushing-at-least-twice-daily. Conclusion Unemployment and EH&E mediated the association between income inequality and toothbrushing. Country-level factors may indirectly impact toothbrushing.

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Efficacy of 1.23% acidulated phosphate fluoride gel on non-cavitated enamel lesions: a randomized clinical trial

Cited by 6 publications

References 19 publications

Bioactive Materials for Caries Management: A Literature Review

Bioactive Materials for Caries Management: A Literature Review

Acidulated phosphate fluoride sebagai bahan pencegahan Karies gigi anak : a scoping review (Laporan Penelitian)

Unemployment and expenditure on health and education as mediators of the association between toothbrushing and global income inequalities

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