Efficacy of 11 anticoagulants for the prevention of venous thromboembolism after total hip or knee arthroplasty: A systematic review and network meta-analysis

Huang, Zhihao; Xu, Xiang; Xu, Dan; Zhao, Pengfei; Zou, Miao

doi:10.1097/md.0000000000032635

Cited by 3 publications

(1 citation statement)

References 64 publications

(65 reference statements)

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“…Para dicha prevención se recomienda el uso de apixaban, rivaroxabán, edoxaban, darexaban y fondaparinux. (8) De ellos, apixaban, rivaroxabán y fondaparinux han demostrado una reducción en la incidencia de TVP. Mientras que dabigatrán, apixaban y la aspirina tienen mayor eficacia en la prevención de EP.…”

Section: Discussionunclassified

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Ygnacio-Mestanza,

Bazualdo-Fiorini,

Pajares-Huaripata

et al. 2024

Salud, Ciencia y Tecnología - Serie de Conferencias

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Venous thromboembolism (VTE) is an important cause of morbidity and mortality with a cardiovascular factor. Its appearance is generally determined by risk factors such as surgery. This occurrence can be avoided in some scenarios thanks to the administration of thromboprophylaxis. Therefore, the objective of the study was to analyze the effectiveness of thromboprophylaxis on the incidence of VTE in post-surgical patients. The study was developed thanks to an analytical approach to information, with the PRISMA methodology of systematic reviews, for which works were retrieved through the PUBMED, Science Direct and Scopus search engines, where 20 academic documents were recognized. It is concluded that thromboprophylaxis reduces the incidence of VTE in post-surgical patients; however, it is recommended to continue with studies to determine the most specific anticoagulant according to the type of surgery.

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Section: Discussionunclassified

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Ygnacio-Mestanza,

Bazualdo-Fiorini,

Pajares-Huaripata

et al. 2024

Salud, Ciencia y Tecnología - Serie de Conferencias

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Resveratrol as an adjuvant prebiotic therapy in the management of pulmonary thromboembolism

SUTEDJA,

TJANDRA,

ODEN

et al. 2024

Minerva Cardiol Angiol

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Influence of Diabetes Mellitus on Postoperative Complications After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis

Hong,

Kwon,

Lee

et al. 2024

Medicina

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Background and Objectives: Total knee arthroplasty (TKA) is an effective treatment option for severe knee osteoarthritis. Understanding the impact of diabetes mellitus (DM) on postoperative outcomes is crucial for improving patient satisfaction after TKA. This study aimed to investigate the influence of DM on postoperative complications and mortality after TKA. Materials and Methods: We conducted a systematic review and meta-analysis by searching relevant studies published before December 2023 in the PubMed, EMBASE, Cochrane Library, Medline, and Web of Science databases. The assessment included demographic data, comorbidities, and postoperative complications after primary TKA for both DM and non-DM patients. The odds ratio (OR) was used to represent the estimate of risk of a specific outcome. Results: Thirty-nine studies were finally included in this meta-analysis. Patients with DM had higher rates of periprosthetic joint infection (OR: 1.71, 95% confidence interval [CI]: 1.46–2.00, p < 0.01) and prosthesis revision (OR: 1.37, 95% CI: 1.23–1.52, p < 0.01). Moreover, patients with DM showed an elevated incidence of pneumonia (OR: 1.54, 95% CI: 1.15–2.07, p < 0.01), urinary tract infection (OR: 1.86, 95% CI: 1.07–3.26, p = 0.02), and sepsis (OR: 1.61, 95% CI: 1.46–1.78, p < 0.01). Additionally, the postoperative risk of cardiovascular (OR: 2.49, 95% CI: 1.50–4.17, p < 0.01) and cerebrovascular (OR: 2.38, 95% CI: 1.48–3.81, p < 0.01) events was notably higher in patients with DM. The presence of DM increased the risk of deep vein thrombosis (OR: 1.58, 95% CI: 1.22–2.04, p < 0.01), but did not lead to an increased risk of pulmonary embolism. Most importantly, DM was associated with a higher mortality rate within 30 days after TKA (OR: 1.27, 95% CI: 1.02–1.60, p = 0.03). Conclusions: Patients with DM exhibited a higher rate of postoperative complications after TKA, and DM was associated with a higher mortality rate within 30 days after TKA. It is crucial to educate patients about the perioperative risk and develop evidence-based guidelines to prevent complications after TKA.

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Efficacy of 11 anticoagulants for the prevention of venous thromboembolism after total hip or knee arthroplasty: A systematic review and network meta-analysis

Cited by 3 publications

References 64 publications

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Thromboprophylaxis to prevent venous thromboembolism in postoperative patients

Resveratrol as an adjuvant prebiotic therapy in the management of pulmonary thromboembolism

Influence of Diabetes Mellitus on Postoperative Complications After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis

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