Efficacy of 2.5% Pimafucin suspension in the treatment of denture stomatitis

Interventions for the Management of Denture Stomatitis: A Systematic Review and Meta‐Analysis

“…The majority of participants were recruited in outpatient clinics at universities or hospitals. 11,[16][17][18][20][21][22][23][29][30][31][32][33][42][43][44][45][46][47] Three studies included institutionalized individuals from geriatric or chronic care hospitals, 15,19,44 and many studies did not describe the setting. [12][13][14]18,[24][25][26][27][28]34…”

“…13,14,[16][17][18]22,[24][25][26][27]31,[35][36][37][38][39]42,43,45,46 Some were 7 to 8 days, 15,32,40,47 and the rest were longer than 15 days, with a maximum of 90 days. 11,12,20,21,23,[28][29][30]33,34,41,44 One study used a single application of the intervention. 19 Most of the studies were blinded for assessment of outcome.…”

“…Of the 35 included trials, 11 did not have data to be entered in the meta-analysis because they presented the results only in figures or graphs or because the data were not usable for statistical analysis. [32][33][34][35][36][37][38][39][40][41]43,44 Of the 24 studies entered into the meta-analysis, 42,[45][46][47] 12 compared an active intervention with placebo, [11][12][13]15,18,19,21,[23][24][25][26]28,30,47 five compared two active interventions, 14,17,22,27,31,42,45,46 and the three remaining trials compared an intervention with no treatment. 16,20,29 For further details, see Table S3.…”

“…The effects of disinfectant solutions on clinical stomatitis and mycological assessment were compared with that of placebo. To evaluate the effect of disinfectant solutions on clinical stomatitis, five studies 12,21,24,25,29,30 were included in a random-effects meta-analysis. Three studies evaluated mycological assessment 11,12,26 in a fixed-effects meta-analysis.…”

The predominant microflora of the palatal mucosa in an elderly island population

“…Staphylococcus aureus, enterobacteria, and shift of the oral flora to higher proportions of gram-negative and anaerobic bacteria have been associated with denture stomatitis, suggesting that fungal growth is not the only etiologic factor (14,24). Additionally, it has been demonstrated that some antifungal drugs may also have antibacterial effects (25).…”