Efficacy of a Brazilian calcium montmorillonite against toxic effects of dietary aflatoxins on broilers reared to market weight

Abstract

1. The protective effect of a natural Brazilian calcium montmorillonite (CaMont) against aflatoxins was studied in broiler chickens. 2. A total of 1056-d-old Cobb male broilers were housed in experimental pens (22 chickens per pen) for 42 d. Three levels of CaMont (0, 2.5 and 5 g/kg) and two levels of aflatoxins (0 and 3 mg/kg) were assayed. Each treatment had 8 replicate pens of 22 broiler chickens each. 3. Of all the chickens tested in the experiment, the ones treated with aflatoxins were the most adversely affected. CaMont treatment at concentrations of 2.5 and 5 g/kg improved body weight of chickens at 42 d of age by 13.3% and 22.7%, increased daily feed intake by 9.7% and 24.7%, and improved the productive efficiency index of chickens by 53% and 66.5%, respectively. 4. Dietary CaMont positively affected parameters such as weight of liver, heart and gizzard; however, serum potassium concentration decreased by 15.3% compared with that of chickens given only the aflatoxin-contaminated diet. 5. CaMont did not cause adverse effects in chickens that did not receive aflatoxins. 6. CaMont at pH 8.5 partially reduced the toxic effects of aflatoxins in broilers when included at levels of 2.5 and 5 g/kg in the diet.

Study on Efficacy of Diatomaceous Earth to Ameliorate Toxic Effects of Aflatoxin on Internal Organ Weights in Broiler Chicken

“…Similar findings have also been reported by earlier workers (Shi et al, 2006;Bailey et al, 2006;Denli et al, 2009, Eckhardt et al, 2014, which could be related to possible role of DAE in ameliorating adverse effects of aflatoxin, as indicated earlier by its absorbent property. However, no change in relative weight of liver, kidney, spleen and bursa of Fabricius in response to incorporation of DAE in AF mixed feed of broilers has also been reported earlier (Modirsanei et al, 2008).…”

Effect of Toxin Binder on Productive Performance of Lactating Friesian Cows

“…Deng et al (2010) pointed that clays contains chemical bonds linked to the active sites of type B of affaltoxin. Eckhardt et al (2014) displayed that clays successfully adsorbed AFB1 in the gastrointestinal tract. The additives of Bentonite were safety for feeding livestock as 20 mg/Kg intake DM for all animal species (EFSA, 2013).…”

“…Bentonite clay is one of the main adsorbent materials in Egypt used to improve feed intake, digestibility of nutrients and daily gain of growing lambs (Salem et al 2001). Bentonite includes layers in its structure and rich in mineral compositions that enhance to absorbance toxic molecules by gut cells (Eckhardt et al 2014, Yarmots, 2014. Bentonite clay act as a reservoir and regulator of ammonia concentration in the rumen and consequently prevented ammonia toxicity and improved urea utilization from solution when concentrate is high and releases it back when concentrate low.…”

In Vitro Binding Potentials of Bentonite, Yeast Cell Wall and Lactic Acid Bacteria for Aflatoxin B1 and Ochratoxin A

“…These mechanisms mostly act by forming chemical bonds between the active sites in AFB1 (the β-D-dicarbonyl groups) and clay soils. The clay soils, especially montmorillonite, have useful effects on AFB1 adsorption by the digestive system in livestock and poultry and can neutralize its harmful effects on health and yield of animals [9]. Nevertheless, this group of adsorbents is of low efficiency in adsorbing other toxins such as OTA [11].…”

“…Among the various clay soil adsorbents, bentonite and its main mineral montmorillonite have received special interest. The layer structure of montmorillonite allows it to swell when it is placed in a liquid environment, and it can thus adsorb AFB1 on its layers and prevent adsorption of AFB1 molecules by cells in the digestive system [9]. The various possible mechanisms by which clay soils may adsorb AFB1 molecules are studied [10].…”