“…Ten of the trials had >100 participants, 28,73,74,76,78,90,91,97,99,101 and 16 provided longer-term data: 10 studies lasting 1 to 2 years, 28,69,73,76,84,92,94,99,103,105 five studies lasting 2 years, 36,78,88,91,97 and one study providing follow-up data at 3 years. Of six studies lasting ≥2 years, 36,78,88,91,97,98 five sustained a clinically meaningful HbA1c reduction (of at least 0.7% from baseline).…”