2017
DOI: 10.1111/avj.12559
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Efficacy of a morantel–abamectin combination for the treatment of resistant ascarids in foals

Abstract: On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel-abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites.

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Cited by 19 publications
(20 citation statements)
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“…For Parascaris , ML drugs, if active against larval stages, will reduce refugia and may increase selection pressure for AR . In the current study, MLs in interval treatment programmes were extensively used by respondents for foals which may be associated with the development of resistance to ivermectin in Parascaris , which has been described recently to occur on Australian stud farms …”
Section: Discussionmentioning
confidence: 83%
“…For Parascaris , ML drugs, if active against larval stages, will reduce refugia and may increase selection pressure for AR . In the current study, MLs in interval treatment programmes were extensively used by respondents for foals which may be associated with the development of resistance to ivermectin in Parascaris , which has been described recently to occur on Australian stud farms …”
Section: Discussionmentioning
confidence: 83%
“…However, resistance of Parascaris spp. has been reported to an abamectin/morantel combination where abamectin alone exhibited poor efficacy [18, 24, 79, 80]. A combination of morantel, oxibendazole and dichlorvos was shown to be effective against cyathostomins, strongylins as well as a benzimidazole-resistant P. equorum [18].…”
Section: Control Of Gins In Horsesmentioning
confidence: 99%
“…However, the majority of equine owners/managers in Australia usually follow a regular treatment interval of 6–8 weeks without any estimation of faecal egg counts (FECs) or consideration of seasonal variation [19]. The intensive use of anthelmintics has driven in the emergence of GIN populations resistant to all major classes of anthelmintics used in Australia, including benzimidazoles, macrocyclic lactones and tetrahydropyrimidines [12, 18, 2024]. Thus, a national survey of the prevalence of anthelmintic resistance (AR) in Australian horses is required for the effective control and management of equine nematodes.…”
Section: Introductionmentioning
confidence: 99%
“…This month's equine study used combination anthelmintics to effectively treat foals with macrocylic lactone (ML)‐resistant Parascaris species . As traditional anthelmintics are becoming less useful in controlling Parascaris species, because of increasing anthelmintic resistance (AR), a strategy used in ruminant grazing to reduce the rate of AR is combining anthelmintics with the same spectrum of activity but different mechanisms of action.…”
mentioning
confidence: 99%
“…This month's equine study used combination anthelmintics to effectively treat foals with macrocylic lactone (ML)-resistant Parascaris species. 7 As traditional anthelmintics are becoming less…”
mentioning
confidence: 99%