Efficacy of Acupuncture Is Noninferior to Nicotine Replacement Therapy for Tobacco Cessation

Wang, Yingying; Liu, Zhao; Wu, Yujuan; Yang, Li; Guo, Lei; Zhang, Haobin; Yang, Jinsheng

doi:10.1016/j.chest.2017.11.015

Cited by 18 publications

(9 citation statements)

References 11 publications

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“…In general, our findings on abstinence rates were consistent with the previous multicenter observational study on acupuncture combined with auricular acupressure from Hong Kong (34.01% at week 8) [12] and the previous randomized controlled trial on acupuncture from China (36.00% at week 8 and 43.00% at week 24) [9]. Our study's smoking cessation rates were noninferior to 8-week nicotine replacement therapy as reported in an earlier clinical trial in China (46.00% at week 8 and 44.00% at week 24).…”

Section: Comparisons With Previous Studiessupporting

confidence: 92%

“…Regarding FTND, a previous clinical trial reported improvements in mean scores over time, from week 8 (posttreatment) to week 24 (follow-up), for both acupuncture and auricular point pressing [ 9 ]. Our results indicated a greater improvement in FTND scores over time, which revealed that acupuncture combined with acupressure might have an effect on nicotine dependence.…”

Section: Discussionmentioning

confidence: 99%

“…A study exploring the neural mechanisms of acupuncture indicated that the immediate effects of acupuncture on smoking cravings were significant and identified the anterior cingulate cortex, insula, prefrontal cortex, visual cortex, and cerebellum as the key brain areas involved in the response [ 7 ]. Previous clinical studies have also shown that acupuncture is effective for smoking cessation [ 8 , 9 ], its treatment effect is noninferior to that of nicotine replacement therapy [ 9 ], and said effect may last for at least 5 years [ 10 ]. Acupuncture is also safe and can relieve withdrawal symptoms [ 8 ] and reduce daily cigarette consumption [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Acupuncture combined with auricular acupressure for smoking cessation and its effects on tobacco dependence and smoking behavior among Hong Kong smokers: a multicenter pilot clinical study

Ho¹,

Ho²,

Wong³

et al. 2022

Chin Med

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Background Acupuncture combined with auricular acupressure has been used as a complementary and alternative treatment for smoking cessation in Hong Kong for over 10 years. This study aimed to investigate the success rates of smoking cessation posttreatment, and to evaluate treatment effects on tobacco dependence, smoking behavior, anxiety levels, and sleep disturbances between successful and unsuccessful quit smokers in Hong Kong. Methods This prospective, multicenter clinical study conducted between September 2020 and February 2022 in Hong Kong was part of the Guangdong-Hong Kong-Macau Greater Bay Area project on smoking cessation. Thirty eligible current smokers (mean age 47.10 years; 40% female) were recruited and received a combination of standardized acupuncture and auricular acupressure treatments twice weekly for 8 weeks. The primary outcome was the success rate of smoking cessation at week 24. The secondary outcomes were the success rates of smoking cessation at weeks 8 and 16, exhaled carbon monoxide (CO) levels, and changes in scores on the Fagerström Test for Nicotine Dependence (FTND), Autonomy Over Smoking Scale (AUTOS), Hamilton Anxiety Rating Scale (HAM-A), Self-rating Anxiety Scale (SAS), and Pittsburgh Sleep Quality Index (PSQI). Adverse events were also recorded. Results Of 30 eligible participants, 28 completed 6 or more treatment sessions; all completed follow-up assessments. At week 24, the success rate of smoking cessation was 46.67%. The successfully quit rates at weeks 8 and 16 were 36.67% and 43.33%, respectively. The overall change in mean FTND scores from baseline improved significantly from weeks 2 to 24 (P < 0.05), with the successful quit group showing significantly greater improvement between weeks 8 and 24 (P < 0.01). Compared with baseline values, there were significant reductions in mean AUTOS scores from weeks 6 to 24 (P < 0.001), with the successful quit group showing greater improvement at weeks 16 (P = 0.04) and 24 (P < 0.001). No significant changes were detected in exhaled CO levels or HAM-A, SAS, and PSQI scores. No study-related adverse events were observed. Conclusions Acupuncture combined with auricular acupressure could be an effective alternative treatment for smoking cessation and reduction of tobacco dependence among Hong Kong smokers. Trial registration Chinese Clinical Trial Registry, No. ChiCTR2000033650. Registered on June 7, 2020. http://www.chictr.org.cn/showproj.aspx?proj=54866

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Section: Comparisons With Previous Studiessupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Acupuncture combined with auricular acupressure for smoking cessation and its effects on tobacco dependence and smoking behavior among Hong Kong smokers: a multicenter pilot clinical study

Ho¹,

Ho²,

Wong³

et al. 2022

Chin Med

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“…During smoking cessation acupuncture significantly improves withdrawal symptoms, including upset, irritability, anxiety, and impatience experienced. However, the precise role of acupuncture for smoking cessation requires further clarification [ 12 , 13 ]. Hyun S et al demonstrate that NRT and behavioral counseling combined with auricular acupuncture are safer and more effective than traditional therapy alone [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

The efficacy and safety of acupuncture and nicotine replacement therapy for smoking cessation: study protocol for a randomized controlled trial

Wang

Dai

Zhang

et al. 2022

Trials

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Introduction Tobacco hazard is one of the most serious public health problems, accounting for up to 6 million deaths worldwide p.a. We aim to determine the efficacy and safety of acupuncture and/or nicotine replacement therapy on smoking cessation. Methods We will recruit 96 participants who are willing to quit smoking by acupuncture and/or nicotine replacement therapy in Chengguan, Xigu and Heping Districts, Lanzhou city, for multicenter randomized, double-blind, double-dummy controlled clinical trial. Following obtained the informed consent forms, all eligible participants will be randomly divided into 4 groups: (1) acupuncture combined with nicotine patch, (2) acupuncture combined with sham nicotine patch, (3) sham acupuncture combined with nicotine patch, and (4) sham acupuncture combined with sham nicotine patch. These participants will be treated with different intervention modalities for 8 weeks and then will be followed-up for 8 weeks. The SPSS 26.0 software will be applied to analyze the clinical effects and adverse reactions of different intervention measures for smoking cessation. Discussion This trial is a prospective, pragmatic, randomized, multicenter trial study protocol. The outcomes will illustrate the efficacy and safety of acupuncture and/or nicotine patches for smoking cessation. Provide smokers with a superior smoking cessation program. Trial registration Chinese Clinical Trial Registry ChiCTR2100042912. Registered on January 31, 2021.

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“…Smoking cessation can significantly reduce the harm of tobacco use. Pharmacotherapy medication, physician counseling, hotline intervention, [4] and acupuncture [5] increase the likelihood of successful quitting. Moreover, considering the very high mobile technology penetration in China, [6] there is a strong opportunity to use mobile Health (mHealth) to support and facilitate tobacco smoking.…”

Section: Introductionmentioning

confidence: 99%

Feasibility and acceptability of using Wi-Fi access points to provide smoking cessation help at 17 airports and 38 railway stations across China

Liu

Wang

Zhou

et al. 2019

Chinese Medical Journal

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Efficacy of Acupuncture Is Noninferior to Nicotine Replacement Therapy for Tobacco Cessation

Cited by 18 publications

References 11 publications

Acupuncture combined with auricular acupressure for smoking cessation and its effects on tobacco dependence and smoking behavior among Hong Kong smokers: a multicenter pilot clinical study

Acupuncture combined with auricular acupressure for smoking cessation and its effects on tobacco dependence and smoking behavior among Hong Kong smokers: a multicenter pilot clinical study

The efficacy and safety of acupuncture and nicotine replacement therapy for smoking cessation: study protocol for a randomized controlled trial

Feasibility and acceptability of using Wi-Fi access points to provide smoking cessation help at 17 airports and 38 railway stations across China

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